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Early Start: Fetuses generate immune response to vaccination

A fetus can manufacture immune cells and antibodies in direct response to vaccine given to the mother during pregnancy.

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Keywords: start, fetuses, generate, immune, response, vaccination, fetuse

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1. MRSA vaccine shows promise in mouse study
   10-30-2006 · EurekAlert!
   By combining the four bacterial surface proteins that generate the strongest immune response in mice, researchers at the University of Chicago have created a vaccine that significantly protects immunized animals from multiple disease-causing, drug-resistant strains of Staphylococcus aureus, the most common cause of hospital-acquired infections and a rapidly spreading source of community-associated illness.
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2. Microbes start immune response by sneaking inside cells
   04-13-2007 · EurekAlert!
   Bacteria that insert themselves inside key front-line immune cells in mice can trigger a strong immune response, according to a new University of Michigan study published online in Immunity. The findings add to an emerging new picture of the immune response that points the way to more effective vaccines and more precisely targeted drugs for autoimmune diseases such as rheumatoid arthritis.
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3. Smallpox outbreak: How long would it take for vaccines to protect people? Would it work?
   04-30-2007 · EurekAlert!
   In the event of a smallpox outbreak in the United States, how long would it take for a vaccine to start protecting Americans by stimulating an immune response? A new national study led by Saint Louis University School of Medicine will attempt to answer this question.
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4. Tumors use enzyme to recruit regulatory T-cells and suppress immune response
   08-16-2007 · EurekAlert!
   One way tumors fly under the radar of the immune system is by using IDO, an enzyme used by fetuses to help avoid rejection, to recruit powerful regulatory T cells that turn down the immune response, researchers say.
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5. Influenza vaccine causes weaker immune response for rural children
   10-22-2007 · EurekAlert!
   Researchers have found that vaccination against influenza strains seems to be more effective in a semi-urban population than in a rural population of schoolchildren in Gabon, Africa, according to an article in the Dec. 1 issue of The Journal of Infectious Diseases. The study suggests that infection with parasites and/or poor nutrition may have an impact on the effectiveness of influenza vaccine.
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6. Influenza vaccine causes weaker immune response for children of rural Gabon than in semi-urban areas
   10-22-2007 · EurekAlert!
   Researchers have found that vaccination against influenza strains seem to be more effective in a semi-urban population than in a rural population of schoolchildren in Gabon, Africa, according to an article in the Journal of Infectious Diseases. The study is one of eight that will be presented and webcast live from the National Institutes of Health on Oct. 22, 2007 as part of the launch of the Council of Science Editors' Global Theme Issue on Poverty and Human Development.
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7. New study finds on/off switch for septic shock
   11-14-2006 · EurekAlert!
   According to a new study, septic shock -- a dangerous, often deadly runaway immune response -- is controlled by a genetic on/off switch. The research also suggests how a drug might temper sepsis. This is the first time this genetic mechanism has been revealed in an experimental animal.
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8. Researchers propose reason for severe side-effects of Northwick Park clinical trial
   01-25-2007 · EurekAlert!
   A possible reason why the Northwick Park clinical trial of the drug TGN1412 in the UK caused multiple organ failure in human volunteers is revealed in research presented today at a conference near Paris. The research shows that stimulating the molecule CD28 on cells that mediate the immune response, known as T cells, can have an adverse effect if these immune cells have been activated and altered by infection or illness in the past.
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9. Vitamin D3 provides the skin with protection from harmful microbes
   02-08-2007 · EurekAlert!
   A new study to be published in the Journal of Clinical Investigation shows that wounding of the skin of humans triggers the production (by skin cells known as keratinocytes) of the active form of vitamin D3, which, in turn, induces an immune response that includes the production of antimicrobial peptides, such as cathelicidin, and the upregulation of receptors that recognize microbial components, such as TR2 and CD14.
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10. Minuscule molecules pack a powerful punch
    04-26-2007 · EurekAlert!
    A role for a microRNA in the immune system has been shown by study of one of the world's first microRNA knockout mouse, reported Friday, April 27, in Science. The microRNA acts as a lynchpin to balance the response of immune defences and the researchers suggest the corresponding human gene will have a similar vital role.
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