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Vorinostat shows anti-cancer activity in recurrent gliomas
06-03-2007 · EurekAlert!North Central Cancer Treatment Group (NCCTG) researchers, based at Mayo Clinic in Rochester, Minn., report that a novel application of the drug vorinostat shows activity in patients with recurrent glioblastoma multiforme.
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Keywords: vorinostat, shows, anti-cancer, activity, recurrent, gliomas, show, anti, cancer, glioma
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- VEGF Trap shows activity in patients with advanced ovarian cancer
06-02-2007 · EurekAlert!
Preliminary results of a randomized, international Phase II trial of VEGF Trap (aflibercept) show activity in patients with recurrent epithelial ovarian cancer (EOC) who had received three or four prior chemotherapy regimens and had become resistant to platinum-based chemotherapy agents. The findings, which are being presented today at the American Society of Clinical Oncology’s annual meeting, may indicate a role for this targeted therapy in women with ovarian cancer who have exhausted all other options.
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- Vaccine for brain tumors shows promising results
11-16-2006 · EurekAlert!
A vaccine for treating a recurrent cancer of the central nervous system that occurs primarily in the brain, known as glioma, has shown promising results in preliminary data from a clinical trial at UCSF Medical Center.
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- New chemotherapy regimen prolongs survival in difficult-to-treat childhood brainstem gliomas
09-25-2007 · EurekAlert!
Spanish researchers told the European Cancer Conference in Barcelona that they have found that a chemotherapy regimen of irinotecan and cisplatin produced rapid clinical responses in childhood brain stem glioma, and shrank the tumors by more than 20 percent in all six children enrolled in a clinical trial.
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- Innovative movies show real-time immune-cell activity within tumors
11-20-2006 · EurekAlert!
Using advanced new microscopy techniques in concert with sophisticated transgenic technologies, scientists have for the first time created three-dimensional, time-lapse movies showing immune cells targeting cancer cells in live tumor tissues. Immune cells called T cells can be seen actively migrating though tissues, making direct contact with tumor cells, and killing them. Insights from this new view of the body's on-board defenses against cancer may open the way for improved immunotherapies to treat the disease.
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- Antibiotic Inhibits Cancer Gene Activity
10-02-2006 · ScienceDaily
A little-known antibiotic shows early promise as an anti-cancer agent, inhibiting a gene found at higher-than-normal levels in most human tumors, according to researchers at the University of Illinois at Chicago College of Medicine.
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- Drug shows activity against brain metastases
06-03-2007 · EurekAlert!
The drug lapatinib shrank tumors and slowed progression of brain metastases in some patients with advanced breast cancer, according to results of a clinical trial being presented by Dana-Farber Cancer Institute scientists at the annual meeting of the American Society of Clinical Oncology.
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- New class of targeted cancer drugs shows promise in slowing progression of recurrent prostate cancer
02-16-2007 · EurekAlert!
A new class of targeted anti-cancer drugs that blocks the human epidermal growth factor (HER) receptor family shows promise in prolonging the lives of patients with recurrent prostate cancer, a new Cedars-Sinai study shows.
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- Innovative device to treat brain cancer shows promise in early studies
05-29-2007 · EurekAlert!
New early data showed that an investigational device that specifically targets rapidly growing cancer cells with intermediate frequency electrical fields -- called Tumor-Treating Fields -- more than doubled the median overall survival rates in patients with recurrent glioblastoma multiforme, the most common and aggressive type of malignant brain tumor.
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- Phase I pharmacokinetic study of ECO-4601, a novel bifunctional targeting agent
10-24-2007 · EurekAlert!
A first-in-class, targeted investigational therapy specifically designed to inhibit a single protein that functions only during cell division shows potent activity in a broad range of cancer cell lines, say researchers presenting at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics.
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- Molecule blocks gene, sheds light on liver cancer
08-01-2007 · EurekAlert!
New research shows how a particular small molecule blocks the activity of a cancer-suppressing gene, allowing liver cancer cells to grow and spread. This molecule is a microRNA, a recently discovered class of tiny molecules used by cells to help control the kinds and amounts of proteins they make. More than 250 different microRNAs have been discovered, and several have been linked to cancer.
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