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Reprogrammed fibroblasts identical to embryonic stem cells
06-06-2007 · EurekAlert!Researchers have manipulated mouse fibroblasts and, without using any eggs or embryos, turned them into cells with such developmental elasticity that they appear identical to embryonic stem cells.
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Keywords: reprogrammed, fibroblasts, identical, embryonic, stem, cells, fibroblast, cell
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Similar news on "Reprogrammed fibroblasts identical to embryonic stem cells":
- A twist of fate -- Reprogrammed fibroblasts resemble embryonic stem cells
06-06-2007 · EurekAlert!
Stem cell biology takes another exciting leap forward as scientists report that normal tissue cells can be reprogrammed to exhibit many of the properties that are characteristic of embryonic stem cells, including the ability to give rise to multiple cell types and contribute to the germline.
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- Reprogrammed adult cells treat sickle-cell anemia in mice
12-06-2007 · EurekAlert!
This is the first proof of principle for using adult cells reprogrammed to an embryonic-stem-cell-like state, combined with gene and cell therapy, for successful disease treatment in mice. Similar "induced pluripotent stem cells" were recently derived with human cells.
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- UCLA stem cell scientists reprogram human skin cells into embryonic stem cells
02-11-2008 · EurekAlert!
UCLA stem cell scientists have reprogrammed human skin cells into cells with the same unlimited properties as embryonic stem cells without using embryos or eggs.
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- A matter of force
05-03-2007 · EurekAlert!
When a cell divides, normally the result is two identical daughter cells. In some cases however, cell division leads to two cells with different properties. This is called asymmetric cell division and plays an important role in embryonic development and the self-renewal of stem cells. Researchers from the European Molecular Biology Laboratory have now worked out the mechanism underlying asymmetric cell division in nematode worms.
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- UCLA scientists produce functioning neurons from human embryonic stem cells
08-07-2007 · EurekAlert!
Scientists with the Institute of Stem Cell Biology and Medicine at UCLA were able to produce from human embryonic stem cells a highly pure, large quantity of functioning neurons that will allow them to create models of and study diseases such as Alzheimer's, Parkinson's, prefrontal dementia and schizophrenia.
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- Researchers reveal repressor protein blocks neural stem cell development
10-10-2007 · EurekAlert!
A protein known to repress gene transcription at the molecular level in a variety of processes also blocks embryonic neural stem cells from differentiating into neurons, according to a study by University of California, San Diego and Howard Hughes Medical Institute researchers published online Oct. 10 in Nature.
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- MIT corrects sickle-cell anemia in mice
12-07-2007 · Massachusetts Institute of Technology (MIT)
MIT researchers have successfully treated mice with sickle-cell anemia in a process that begins by directly reprogramming the mice's own cells to an embryonic-stem-cell-like state, without the use of eggs.
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- Gene Key To Taste Bud Development Identified
10-02-2006 · ScienceDaily
Scientists have identified a gene that controls the development of taste buds. The gene, SOX2, stimulates stem cells on the surface of the embryonic tongue and in the back of the mouth to transform into taste buds, according to the researchers. Stem cells are immature cells that can develop into several different cell types depending on what biochemical instructions they receive.
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- Mass. General researchers identify master cardiac stem cell
11-22-2006 · EurekAlert!
Researchers from the Massachusetts General Hospital Cardiovascular Research Center have discovered what appears to be a master cardiac stem cell, capable of differentiating into the three major cell types of the mammalian heart. In a report to appear in the journal Cell, receiving early online release, they describe identifying these progenitor cells in mice, cloning them from embryonic stem cells, and showing that cloned cells can differentiate into cardiac muscle, smooth muscle or endothelial cells.
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- Cells take risks with their identities
07-12-2007 · EurekAlert!
Contrary to textbook models, many genes that should be "off" in embryonic stem cells and specialized adult cells remain primed to produce master regulatory proteins, leaving those cells vulnerable to identity changes. The genes encoding the master regulators of cell fate begin making RNA templates for these proteins, though a control mechanism stops them from finishing the job.
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