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UCLA researchers reprogram normal tissue cells into embryonic stem cells
06-06-2007 · EurekAlert!Researchers at the Institute for Stem Cell Biology and Medicine at UCLA were able to take normal tissue cells and reprogram them into cells with the same unlimited properties as embryonic stem cells, the cells that are able to give rise to every cell type found in the body.
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Keywords: ucla, researchers, reprogram, normal, tissue, cells, embryonic, stem, researcher, cell
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- Simple recipe turns human skin cells into embryonic stem cell-like cells
11-20-2007 · EurekAlert!
A simple recipe -- including just four ingredients -- can transform adult human skin cells into cells that resemble embryonic stem cells, researchers report in an immediate early publication of the journal Cell, a publication of Cell Press. The converted cells have many of the physical, growth and genetic features typically found in embryonic stem cells and can differentiate to produce other tissue types, including neurons and heart tissue, according to the researchers.
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- Human embryonic stem cell -- derived bone tissue closes massive skull injury
12-02-2007 · EurekAlert!
There are mice in Baltimore whose skulls were made whole again by bone tissue grown from human embryonic stem cells. Healing critical-size defects, which would not otherwise heal on their own, in intramembraneous bone, the flat bone type that forms the skull, is a vivid demonstration of new techniques devised by researchers using hESCs for tissue regeneration.
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- UCLA stem cell scientists reprogram human skin cells into embryonic stem cells
02-11-2008 · EurekAlert!
UCLA stem cell scientists have reprogrammed human skin cells into cells with the same unlimited properties as embryonic stem cells without using embryos or eggs.
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- A twist of fate -- Reprogrammed fibroblasts resemble embryonic stem cells
06-06-2007 · EurekAlert!
Stem cell biology takes another exciting leap forward as scientists report that normal tissue cells can be reprogrammed to exhibit many of the properties that are characteristic of embryonic stem cells, including the ability to give rise to multiple cell types and contribute to the germline.
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- Tissue Geometry Plays Crucial Role In Breast Cell Invasion
10-13-2006 · ScienceDaily
Researchers with the U.S. Department of Energy's Lawrence Berkeley National Laboratory have created a first-of-its-kind model for studying how breast tissue is shaped and structured during development. The model may shed new light on how the misbehavior of only a few cells can facilitate metastatic invasion because it shows that the development of breast tissue, normal or abnormal, is controlled not only by genetics, but also by geometry.
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- Scientists overcome obstacles to stem cell heart repair
12-12-2007 · EurekAlert!
Scientists have overcome two significant obstacles on the road to harnessing stem cells to build patches for damaged hearts. Presenting the research at a UK Stem Cell Initiative conference the researchers will explain how they have made significant progress in maturing beating heart cells derived from embryonic stem cells and in developing the physical scaffolding that would be needed to hold the patch in place in the heart in any future clinical application.
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- Gene Key To Taste Bud Development Identified
10-02-2006 · ScienceDaily
Scientists have identified a gene that controls the development of taste buds. The gene, SOX2, stimulates stem cells on the surface of the embryonic tongue and in the back of the mouth to transform into taste buds, according to the researchers. Stem cells are immature cells that can develop into several different cell types depending on what biochemical instructions they receive.
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- Mass. General researchers identify master cardiac stem cell
11-22-2006 · EurekAlert!
Researchers from the Massachusetts General Hospital Cardiovascular Research Center have discovered what appears to be a master cardiac stem cell, capable of differentiating into the three major cell types of the mammalian heart. In a report to appear in the journal Cell, receiving early online release, they describe identifying these progenitor cells in mice, cloning them from embryonic stem cells, and showing that cloned cells can differentiate into cardiac muscle, smooth muscle or endothelial cells.
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- Reprogramming the debate: stem-cell finding alters ethical controversy
11-20-2007 · EurekAlert!
When University of Wisconsin-Madison researchers succeeded in reprogramming skin cells to behave like embryonic stem cells, they also began to redefine the political and ethical dynamics of the stem-cell debate, a leading bioethicist says.
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- Cannibalistic signals help mammalian embryos develop normally
03-08-2007 · UT Southwestern Medical Center
A cannibalistic process called autophagy spurs dying embryonic stem cells to send “eat me” and "come get me" signals to have their corpses purged, a last gasp that paves the way for normal mammalian development, UT Southwestern Medical Center researchers have found.
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