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Loss of stem cells correlates with premature aging in animal study

06-06-2007 · EurekAlert!

Researchers at the Abramson Family Cancer Research Institute of the University of Pennsylvania have found that deleting a gene important in embryo development leads to premature aging and loss of stem cell reservoirs in adult mice. This gene, ATR, is essential for the body's response to damaged DNA, and mutations in proteins in the DNA damage response underlie certain types of cancer and other disorders in humans.

Keywords: loss, stem, cells, correlates, premature, aging, animal, study, cell, correlate

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