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Study shows big power of small RNAs, not just proteins, in halting cancer

CSHL researchers have identified a family of micro RNAs that enable a known tumor suppressor network to fight cancer growth.

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Keywords: study, shows, big, power, rnas, proteins, halting, cancer, show, rna, protein

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Similar news on "Study shows big power of small RNAs, not just proteins, in halting cancer":

1. New class of RNA molecules may be important in human cancer
   09-11-2007 · EurekAlert!
   New research shows that an obscure form of RNA, part of the protein-making machinery in all cells, might play an important role in human cancer. These ultraconserved noncoding RNAs have been considered "junk" by some researchers, but a new report in the September issue of the journal Cancer Cell indicates that this may not be the case.
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2. First-ever study: lack of critical lubricant causes wear in joints
   11-06-2007 · EurekAlert!
   For the first time, researchers have linked increased friction with early wear in the joints of animals. Work led by Brown University physician and engineer Gregory Jay, MD, shows mice that do not produce the protein lubricin begin to show wear in their joints less than two weeks after birth. This finding not only points up the protective power of lubricin but also suggests that it could be used to prevent joint wear after an injury.
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3. Researchers find level of special protein is critical to proper formation of muscles
   04-23-2007 · EurekAlert!
   Proper formation of the proteins that power heart and skeletal muscle seems to rely on a precise concentration of a "chaperone" protein known as UNC-45, according to a new study.This basic discovery may have important implications for understanding and eventually treating heart failure and muscle wasting elsewhere in the body resulting from burns, brain trauma, diabetes, cancer and the effects of aging.
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4. CSHL researchers show RNA splicing factor may be new target for cancer therapy
   02-18-2007 · EurekAlert!
   New results in the field of RNA research establish that the RNA splicing factor SF2/ASF can act as a cancer-causing protein by changing the alternative splicing of other genes critical for growth-control of cells.
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5. Novel MS drug shows promise in 2 lethal leukemias
   08-28-2007 · EurekAlert!
   A new study suggests that an experimental drug being tested for the treatment of multiple sclerosis and to prevent organ rejection might also help people with certain deadly forms of chronic and acute leukemia. The laboratory and animal study focused on the drug, called fingolimod. Researchers said it might help patients with advanced chronic myelogenous leukemia or acute lymphocytic leukemia, and whose cancer cells show a particular genetic change called the Philadelphia chromosome.
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6. New antibody for EGFR causes lung cancer regression
   01-25-2007 · EurekAlert!
   Mutant forms of the protein EGFR are involved in lung cancer development in many individuals, but not all individuals express the same mutant EGFR. A new study shows that both a mouse EGFR-specific antibody (mAb806) and its humanized form (ch806) cause lung tumor regression in two mouse models of lung cancer, leading to the suggestion that ch806 might provide a new approach to treat patients with lung cancer driven by mutant forms of EGFR.
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7. New neuroimaging study identifies 'brain signature' for cigarette cravings
   12-18-2007 · EurekAlert!
   A new brain imaging study by researchers in the Abramson Cancer Center of the University of Pennsylvania shows that cigarette cravings in smokers who are deprived of nicotine are linked with increased activation in specific regions of the brain. Using a novel method of measuring brain blood flow developed at Penn, this study is the first to show how abstinence from nicotine produces brain activation patterns that relate to urges to smoke.
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8. Novel EGFR antibody outperforms cetuximab in mouse model of lung cancer
   01-26-2007 · EurekAlert!
   A study conducted at the Dana-Farber Cancer Institute and the Ludwig Center at Dana-Farber/Harvard Medical School now suggests that antibodies binding a particular protein conformation, caused by hyperactivation, might have distinct therapeutic advantages over antibodies, like cetuximab, that bind to wild-type (normal) target proteins.
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9. 'Bridge' protein spurs deadliest stages of breast cancer
   02-21-2007 · EurekAlert!
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10. Novel drug preventing protein recycling shows potential for treating leukemia
    04-19-2007 · EurekAlert!
    Researchers from the Children's Cancer Hospital at The University of Texas M. D. Anderson Cancer Center have found that a novel targeted therapy effectively treats acute leukemia in animal models by preventing cancer cells from being purged of damaged proteins.
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