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Dartmouth professor makes case for ethically universal stem cell lines
06-07-2007 · EurekAlert!A recent paper in Nature Review Genetics considers six current approaches to deriving human embryonic stem cell (hESC) lines. "I think we can pursue hESC research and also respect the sensitivities of our fellow citizens. It's not impossible to do both," says the researcher.
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08-06-2007 · EurekAlert!
When it comes to generating neurons, researchers have found that not all embryonic stem cell lines are equal. In comparing neurons generated from two NIH-approved embryonic stem cell lines, scientists have uncovered significant differences in the mature, functioning neurons generated from each line. The discovery implies that culture conditions during ES cell generation -- which have yet to be identified -- can influence the developmental properties of human ES cells.
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Researchers at Penn Vet have demonstrated a new strategy for genetic modification of large animals by employing a virus that transfers genetic modifications to male reproductive cells, which passes naturally to offspring. Scientists at the Center for Animal Transgenesis and Germ Cell Research at Penn introduced adeno-associated virus to germline stem cells in goats and mice. AAV stably transduced male germ line stem cells and led to transgene transmission through the male germ line.
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