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Experts call for urgent research into antiepileptic drugs given to children
06-07-2007 · EurekAlert!Researchers have discovered a five-fold increase in newer antiepileptic drugs given to children, despite the fact that their long-term safety has not been established. They've now called for urgent research into the top three. This comes hard on the heels of a report by the European Medicines Agency, which highlighted the need for further research into 21 antiepileptic drugs for children but didn't state which ones should be prioritised.
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Keywords: experts, call, urgent, research, antiepileptic, drugs, children, expert, drug
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- Experts call for urgent research into anti-epileptic drugs given to children
06-07-2007 · EurekAlert!
Researchers have discovered a five-fold increase in newer anti-epileptic drugs given to children, despite the fact that their long-term safety has not been established. They've now called for urgent research into the top three. This comes hard on the heels of a report by the European Medicines Agency, which highlighted the need for further research into 21 anti-epileptic drugs for children but didn't state which ones should be prioritized.
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- Tiny tweezers and yeast help St. Jude show how cancer drug works
07-09-2007 · EurekAlert!
The annoying bulges of an over-wound telephone cord that shorten its reach and limit a caller's motion help to explain why drugs called camptothecins are so effective in killing cancer cells, according to investigators at St. Jude Children's Research Hospital and Delft University of Technology.
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- Experts call for better research into link between women's hormones and mood disorders
12-12-2007 · EurekAlert!
In a recently published study, women's health experts from the University of Alberta argue there is an urgent need for carefully designed, gender-specific research to better understand the relationship of female sex hormones to mood states and disorders. "The reasons for the gender disparity in rates of depression are not completely understood," says Kathy Hegadoren, the Canada Research Chair in Stress Disorders in Women at the University of Alberta.
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- Child mental health experts issue psychiatric medication treatment guidelines for preschoolers
12-03-2007 · EurekAlert!
The number of preschool-age children being treated with stimulants, antidepressants and other psychiatric drugs is on the rise, despite limited research and a lack of clinical practice guidelines. In a first step toward standardizing treatment approaches, child mental health professionals from the Bradley Hasbro Children's Research Center and 11 other institutions have developed recommendations for specific disorders to help clinicians who are considering medications for children ages 3 to 6.
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- Kenyan malaria success strengthens call for free insecticide-treated nets for all
08-17-2007 · EurekAlert!
Experts have today called for international agencies to provide insecticide-treated bed nets for all children in Africa as the most equitable way of tackling malaria. Their call is supported by new research co-funded by the Wellcome Trust showing how successful a scheme run by the Kenyan government has been at distributing the nets.
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- Cancer drug side effect caused by cell 'pump' problem
12-05-2006 · EurekAlert!
A troublesome side effect caused by some cancer drugs appears to be caused by a broken "pump" in the liver that fails to push these medicines into a "drain," according to investigators at St. Jude Children's Research Hospital.
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- Plant pathogen yields substance to fight neuroblastoma
01-17-2008 · EurekAlert!
Drug treatment of neuroblastoma, a tumor of the nervous system in children, poses major problems. Therefore, scientists at the German Cancer Research Center have been searching for substances that are suitable as a basis for developing better drugs. Now they have found a candidate: HC-toxin, which is isolated from a fungal plant pathogen. The substance from the maize pathogen reprograms neuroblastoma cells in such a way that they behave almost like healthy cells again.
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- National experts and nonprofit organizations call to end FDA user fees and to improve drug safety
03-14-2007 · EurekAlert!
Opposition to current drug safety legislation is growing, as a group of 22 experts on drug safety and regulation and a coalition of 12 patient, consumer, science, and public health organizations issue two separate open letters to lawmakers. The letters asks Congress to not reauthorize the user fees legislation (PDUFA) that finances the FDA’s review of new drugs, and calls for substantial changes to drug safety legislation introduced by Senators Kennedy and Enzi.
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- St. Jude shows gene test not needed if cancer drug given in low doses
06-19-2007 · EurekAlert!
Investigators at St. Jude Children's Research Hospital have shown that when the cancer drug irinotecan is given in low doses for multiple days, it eliminates the need to delay treatment to perform costly genetic testing that determines if the patient is at risk for serious treatment side effects, such as neutropenia.
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- Other highlights in JNCI, June 26
06-26-2007 · EurekAlert!
Also in the June 26 JNCI are a study of sexual function in men taking a potential prostate cancer prevention drug, a review of the use surrogate endpoint in clinical cancer research, and a more efficient clinical trial design for testing targeted drugs.
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