Daily non-political popular news in brief.

Combination therapy reduces tumor resistance to radiation

Radiation is used to treat a variety of tumors as it causes hypoxia and tumor cell death. Recently, radiation-induced hypoxia was shown to trigger tumor resistance to radiation via the activation of new blood vessel formation (angiogenesis). In a new JCI study, researchers show that a combination of radiation treatment and the use of angiogenesis inhibitors such as canstatin is able to overcome HIF-1-dependent tumor survival and increase tumor cell death in mice.

Read more »

Keywords: combination, therapy, tumor, resistance, radiation

« Previous | Next »

Similar news on "Combination therapy reduces tumor resistance to radiation":

1. JCI table of contents: June 7, 2007
   06-07-2007 · EurekAlert!
   This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published online June 7, 2007, in the JCI, including: "Combination therapy reduces tumor resistance to radiation"; "Improved prediction of prostate cancer recurrence"; "Role of GM-CSF in the immune response to tumors"; "Protein C signaling impacts inflammatory bowel disease"; "Iron imbalance in anemia: Hints from HIF"; and "Phosphorylation state of eNOS is key to blood vessel function."
   Similar news · Read more »
   
2. Scientists follow familiar TRAIL to new cancer therapy
   07-09-2007 · EurekAlert!
   A new study identifies a combination therapy that may sensitize human cancer cells to a promising treatment currently being used in clinical trials. The research, published in the July issue of the journal Cancer Cell, published by Cell Press, provides a pharmacological method for enhancing the potency and effectiveness of a tumor necrosis factor death receptor ligand against a variety of human cancers.
   Similar news · Read more »
   
3. Penn researchers identify new combination therapy that promotes cancer cell death
   07-16-2007 · EurekAlert!
   To test the ability of combined therapy, researchers administered TRAIL, a tumor necrosis factor, and sorafenib, an inhibitor currently used to treat renal cancer, to mice with colon carcinomas. It reduced the size of tumors in mice with few side effects
   Similar news · Read more »
   
4. Scripps research combination therapy obliterates new vessel growth in tumors and retinopathy
   01-09-2007 · EurekAlert!
   Using a new and dramatically effective treatment approach, scientists at the Scripps Research Institute have for the first time achieved complete inhibition of new blood vessel growth in animal models of a highly vascular brain tumor and of neovascular eye diseases with little or no effect on normal tissue vasculature.
   Similar news · Read more »
   
5. Experimental anti-cancer drug made from corn lillies kills brain tumor stem cells
   08-30-2007 · EurekAlert!
   A drug that shuts down a critical cell-signaling pathway in the most common and aggressive type of adult brain cancer successfully kills cancer stem cells thought to fuel tumor growth and help cancers evade drug and radiation therapy, a Johns Hopkins study shows.
   Similar news · Read more »
   
6. Henry Ford Hospital expands research on gene and radiation therapy for prostate cancer
   02-06-2008 · EurekAlert!
   Henry Ford Hospital is embarking on an expanded major clinical trial involving the use of gene therapy in combination with radiation therapy, to determine if the combined treatment is more effective than radiation therapy alone for patients with intermediate risk prostate cancer.The clinical trial is part of a $9 million grant from the National Cancer Institute awarded to Henry Ford to study the effectiveness of gene therapy to treat prostate cancer.
   Similar news · Read more »
   
7. Combination therapy shows improvement for breast cancer patients
   12-01-2006 · EurekAlert!
   Giving radiation therapy and chemotherapy at the same time after a lumpectomy helps keep breast cancer from returning locally, according to a study published in the Dec. 1 issue of the International Journal of Radiation Oncology*Biology*Physics, the official journal of ASTRO.
   Similar news · Read more »
   
8. Proton beam therapy may improve treatment of rare but aggressive tumor
   11-20-2006 · EurekAlert!
   Proton beam radiation therapy, a very precise type of radiation treatment, may be an effective treatment for advanced adenoid cystic carcinoma that has spread to the cranial base.
   Similar news · Read more »
   
9. Combination therapy spares some head and neck patients from surgery
   01-19-2007 · EurekAlert!
   Giving patients with head and neck cancer a combination of chemotherapy and radiation therapy controls the cancer and allows many patients to avoid additional surgery to the neck, according to a study presented at the plenary session today at the Multidisciplinary Head and Neck Cancer Symposium in Rancho Mirage, Calif., co-sponsored by the American Society for Therapeutic Radiology and Oncology, the American Society of Clinical Oncology and the American Head and Neck Society.
   Similar news · Read more »
   
10. Guided radiation therapy for prostate cancer prevents damage to surrounding organs
    10-28-2007 · EurekAlert!
    Oregon Health & Science University Cancer Institute researchers have found that highly targeted radiation therapy for prostate cancer can ensure that the majority of persons with this tumor will not have any long-term rectal damage.
    Similar news · Read more »