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Drug slows and may halt Parkinson's disease
06-10-2007 · EurekAlert!Northwestern University researchers have discovered a drug that slows -- and may even halt -- the progression of Parkinson's disease. The drug rejuvenates aging dopamine cells, whose death in the brain causes the symptoms of this devastating and widespread disease.
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- Study of the drug, Isradipine, to determine if it slows or prevents Parkinson's disease
06-13-2007 · EurekAlert!
Gloria E. Meredith, Ph.D., collaborated with D. James Surmeier, Ph.D. and others at Northwestern University to study the drug, Isradipine, and its effects on Parkinson's disease. Dr. Meredith studies a chronic mouse model that mimics the signs and symptoms of Parkinson's disease. The scientists joined together to see if the drug could stop cells from dying in the mouse model. Findings indicated that isradipine slowed the disease process and destruction of the dopamine-producing neurons.
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- Drug helps prevent hip fractures in Parkinson disease
03-19-2007 · EurekAlert!
A drug used to strengthen bone has been found to help reduce the high incidence of hip fractures among people with Parkinson disease, according to a study published in the March 20, 2007, issue of Neurology, the scientific journal of the American Academy of Neurology.
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- Proteins important in Alzheimer's, Parkinson's disease travel in the slow lane
04-17-2007 · EurekAlert!
Using a novel video-imaging system, researchers at the University of Pennsylvania School of Medicine have been able to observe proteins important in Alzheimer's and Parkinson's disease moving along axons, extensions of nerve cells that carry proteins away from the cell body. Understanding this process of axonal transport is important for studying many neurodegenerative diseases.
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- Interferon does not slow or stop hepatitis C from worsening, study finds
11-08-2007 · EurekAlert!
Interferon does not slow or halt the progression of chronic hepatitis C and advanced liver disease in patients who haven't responded to previous attempts to eradicate the disease, a national study has found. Patients who were treated with interferon did experience a significant decrease in viral levels and liver inflammation, but the trial unequivocally demonstrated that treatment with interferon does not prevent the worsening of liver disease in patients who've failed prior treatments.
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- UIC chemists characterize Alzheimer's neurotoxin structure
12-03-2007 · EurekAlert!
A team of UIC chemists has characterized the molecular structure of the intermediate stage of plaque-forming amyloid fibrils, believed to cause Alzheimer's disease. The finding may lead to new drug targets for this and other amyloid diseases, such as Parkinson's and Creutzfeldt-Jakob.
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- Study identifies novel Parkinson's disease drug target
06-21-2007 · EurekAlert!
Researchers at the MassGeneral Institute for Neurodegenerative Disease (MGH-MIND) have identified a potential new drug target for the treatment of Parkinson's disease and possibly for other degenerative neurological disorders.
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- Drug reduces daily 'off' time for Parkinson patients
04-02-2007 · EurekAlert!
Parkinson disease patients taking the drug, ropinirole 24-hour prolonged release significantly reduced their daily "off" time in which Parkinson's symptoms like tremor, slowness, stiffness and walking difficulty return as drugs wear off, according to a study published in the April 3, 2007, issue of Neurology, the scientific journal of the American Academy of Neurology.
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- Researchers identify protein pathway involved in Parkinson disease development
06-18-2007 · EurekAlert!
Scientists have found a novel signaling pathway in cells that is altered by genetic mutations recently identified in Parkinson disease development. These new findings show how the mutations affect cellular function and could provide a target for drug therapies to treat the disease.
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- Learning slows physical progression of Alzheimer's disease
01-23-2007 · EurekAlert!
Learning appears to slow the development of two brain lesions that are the hallmarks of Alzheimer's disease, scientists at UC Irvine have discovered. The finding suggests that the elderly, by keeping their minds active, can help delay the onset of this degenerative disease.
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- For treating advanced Parkinson's, new research points to serotonin
02-04-2008 · EurekAlert!
Studies in a mouse model of Parkinson's disease show that side effects caused by repeated use of the drug L-DOPA can be minimized by blocking the serotonin 1B receptor. The finding, reported by researchers at Rockefeller University and the Karolinska Institute, suggests that targeting the 1B receptor may provide an alternative approach for treating advanced Parkinson's disease.
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