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In nature, proteins sweep up nanoparticles
06-14-2007 · EurekAlert!Here's a pollution-control tip from nature: Deep inside a flooded mine in Wisconsin, scientists from several institutions including the US Department of Energy's Lawrence Berkeley National Laboratory have discovered a world in which bacteria emit proteins that sweep up metal nanoparticles into immobile clumps. Their finding may lead to innovative ways to remediate subsurface metal toxins.
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Keywords: nature, proteins, sweep, nanoparticles, protein, nanoparticle
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- Pairing Nanoparticles with Proteins
06-27-2007 · Brookhaven National Laboratory
In groundbreaking research, scientists have demonstrated the ability to strategically attach gold nanoparticles - particles on the order of billionths of a meter - to proteins so as to form sheets of protein-gold arrays. The nanoparticles and methods to create nanoparticle-protein complexes can be used to help decipher protein structures, to identify functional parts of proteins, and to "glue" together new protein complexes.
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- New hope for Huntington's sufferers
08-22-2007 · EurekAlert!
A major breakthrough in the understanding and potential treatment of Huntington's disease has been made by scientists at the University of Leeds. Researchers in the university's Faculty of Biological Sciences have discovered that one of the body's naturally occurring proteins is preventing 57 genes from operating normally in the brains of Huntington's sufferers. In addition, the destructive nature of this protein could potentially be halted using drugs that are already being used to help cancer patients.
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- Oncoproteins double-team and destroy vital tumor-suppressor
02-14-2008 · EurekAlert!
Two previously unconnected cancer-promoting proteins team up to ambush a critical tumor suppressor by evicting it from the cell's nucleus and then marking it for death by a protein-shredding mechanism, a team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in the Feb. 10 issue of Nature Cell Biology.
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- Silencing small but mighty cancer inhibitors
12-10-2007 · EurekAlert!
Researchers from Johns Hopkins and the University of Pennsylvania have uncovered another reason why one of the most commonly activated proteins in cancer is in fact so dangerous. As reported in Nature Genetics this week, the Myc protein can stop the production of at least 13 microRNAs, small pieces of nucleic acid that help control which genes are turned on and off.
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- Speeding 'fingertip' discovery -- 20 years of protein info in 1 place
04-22-2007 · EurekAlert!
Researchers at Johns Hopkins took advantage of a new technique that reads the makeup of proteins to identify nearly all chemical changes nature makes by adding phosphate to proteins manufactured in human cells.
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- Researchers use new approach to predict protein function
07-11-2007 · EurekAlert!
In a paper published online this month in the journal Nature Chemical Biology, researchers report that they have developed a way to determine the function of some of the hundreds of thousands of proteins for which amino acid sequence data are available, but whose structure and function remain unknown.
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- Global ocean sampling expedition
03-13-2007 · EurekAlert!
The Sorcerer II GOS expedition, data sampling and analysis is described. The immense diversity in the sequence data required novel comparative genomic assembly methods, which uncovered genomic differences that marker-based methods could not. The GOS data identified 6.12 million predicted proteins covering nearly all known prokaryotic protein families, and several new families. This almost doubles the number of known proteins and shows that we are far from identifying all the proteins in nature.
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- University of Pennsylvania researchers zero in on the tiniest members in the war on cancer
12-13-2007 · EurekAlert!
Researchers from the University of Pennsylvania and Johns Hopkins University have uncovered another reason why one of the most commonly activated proteins in cancer is so dangerous. As reported in Nature Genetics this week, the Myc protein can stop the production of at least 13 microRNAs, small pieces of nucleic acid that help control which genes are turned on and off.
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- Fantastic voyage: Drug delivery by a nanoparticle
02-13-2008 · Massachusetts Institute of Technology (MIT)
An image portrays targeted nanoparticles delivering high doses of chemotherapy to cancer cells. A team including MIT Institute Professor Robert Langer has demonstrated the precision required to engineer a nanoparticle that is effective in targeted drug delivery.
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- Gold nanoparticles may pan out as tool for cancer diagnosis
07-31-2007 · EurekAlert!
When it comes to searching out cancer cells, gold may turn out to be a precious metal. Purdue University researchers have created gold nanoparticles capable of identifying marker proteins making the tiny particles a potential tool to better diagnose and treat breast cancer.
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