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Ultra deep sequencing identifies HIV drug resistance at early stage
06-15-2007 · EurekAlert!Rare, previously undetectable drug-resistant forms of HIV have been identified by Yale School of Medicine researcher Michael Kozal, M.D., using an innovative genome sequencing technology that quickly detects rare viral mutations.
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Keywords: ultra, deep, sequencing, identifies, hiv, drug, resistance, stage, identify
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- 454 sequencing identifies HIV drug resistance at early stage
06-15-2007 · EurekAlert!
454 Life Sciences, a member of the Roche group, and a Yale School of Medicine researcher today announced that they have used the company's Genome Sequencer system to identify previously undetectable rare drug resistant HIV variants in samples from an earlier performed clinical trial.
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- Penn researchers develop new method for screening drug-resistant forms of HIV
06-28-2007 · EurekAlert!
Existing methods of detecting drug-resistant forms of HIV are expensive, time consuming and often fail to identify small populations of drug-resistant HIV. Now, researchers have developed a drug resistance screening method that analyzes multiple HIV variants at the same time, while also saving time and money.
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- World Health Organization's plan to monitor HIV drug resistance in Botswana likely to fail
01-16-2007 · EurekAlert!
A World Health Organization plan to track transmitted resistance to HIV drugs in Botswana could fail because the threshold the organization has set is too high, according to new UCLA research.
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- Drug warning prompts treatment changes for those infected with hepatitis B and HIV
06-20-2007 · EurekAlert!
Cross-resistance alarms raised earlier this year by Johns Hopkins researchers about a widely used antiviral therapy for hepatitis B liver infections have prompted swift treatment revisions by the drug's maker and governmental agencies.
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- Nepalese researchers identify cost-effective treatment for drug-resistant typhoid
06-26-2007 · EurekAlert!
New research carried out by researchers in Nepal has shown that a new and affordable drug, Gatifloxacin, may be more effective at treating typhoid fever than the drug currently recommended by the World Health Organization. The study, funded by the Wellcome Trust, has implications for the treatment of typhoid particularly in areas where drug resistance is a major problem.
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- World AIDS Day: HIV prevention, diagnosis and treatment
11-30-2007 · EurekAlert!
On December 1, PLoS Medicine is publishing a collection of research articles and commentary, as well as an editorial to mark World AIDS Day 2007. In this release: Men who have sex with men face high AIDS risk in developing countries; Women disclose their HIV status at three key times around childbirth; Unnoticed mutation in AIDS virus can cause drug resistance; and HIV confirmatory test can also estimate recent infections.
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- Support for chromosomal theory of cancer found in cancers' development of drug resistance
06-27-2007 · EurekAlert!
Most cancer researchers are convinced that cancer results from a handful of genetic mutations that kick a cell into uncontrolled growth. UC Berkeley genetics researcher Peter Duesberg disagrees, and finds support for his "chromosomal" theory of cancer in the development of drug resistance by many cancers. While his theory implies their is no magic bullet against cancer, it does provide ways to detect cancer at an early stage.
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- Hepatitis B drug creates HIV resistance
07-14-2007 · Science News Online
A hepatitis B drug spurs resistance to HIV drugs in people infected with both diseases.
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- HIV drug resistance risk in mothers reduced by combination of common drugs
11-09-2007 · EurekAlert!
Adding a single dose of two common anti-HIV drugs can prevent HIV-positive pregnant women from developing resistance to an entire class of drugs, potentially improving future treatment options.Providing tenofovir and emtricitabine with nevirapine during labor greatly reduces the extent of resistance to non-nucleoside reverse transcriptate inhibitors, such as nevirapine, which HIV-positive women take to lower the risk of mother-to-child transmission during childbirth.
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- Emergence of recombinant forms of HIV: dynamics and scaling
10-26-2007 · EurekAlert!
The new model provides a framework for predicting the development of multi-drug resistance in HIV patients.
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