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Scientists Convert Modern Enzyme into its Hypothesized Ancestor

10-30-2006 · Brookhaven National Laboratory

By making a single substitution in the amino acid sequence of a modern enzyme, scientists have changed its function into that of a theoretical distant ancestor, providing the first experimental evidence for the common origin of the two distinct enzyme types. The research, conducted by a team that includes scientists from the U.S. Department of Energy's Brookhaven National Laboratory and the Karolinska Institute in Stockholm, Sweden, will be published online the week of October 30, 2006, by the P

Keywords: scientists, convert, modern, enzyme, hypothesized, ancestor, scientist

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