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Family structure size could affect breast cancer risk prediction accuracy for BRCA gene testing

06-19-2007 · EurekAlert!

Researchers have found that the probability of the breast cancer gene mutation BRCA among women with a history of breast cancer is greater when the number of older, female relatives in the family is smaller, according to a study in the June 20 issue of JAMA. This finding may challenge the accuracy of some breast cancer prediction models, which may not take family structure into account.

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Keywords: family, structure, size, affect, breast, cancer, risk, prediction, accuracy, brca, gene, testing

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