Daily non-political popular news in brief.
Scripps research scientists show protein accelerates breast cancer progression in animal models
06-20-2007 · EurekAlert!Scientists at the Scripps Research Institute have shown for the first time that a cytokine called pleiotrophin stimulates the progression of breast cancer in both animal and cell culture models. The study, which tested three separate models to determine the role of inappropriate expression of pleiotrophin, found that it produced striking increases in aggressiveness of the breast cancer cells themselves.
Read more »
Keywords: scripps, research, scientists, show, protein, accelerates, breast, cancer, progression, animal, models, scripp, scientist, accelerate, model
« Previous | Next »
Similar news on "Scripps research scientists show protein accelerates breast cancer progression in animal models":
- Murder mystery solved
09-20-2007 · EurekAlert!
Thousands of people die from strokes and heart attacks within 24 hours of a spike in microscopic pollution. Scientists couldn't figure out why. New research from Northwestern University has found that these tiny pieces of soot spur hyperclotting of the blood, resulting in heart attacks and strokes for people at risk. Previous epidemiological research has linked the pollution to cardiovascular death and disease, but this is the first study to show how it actually happens in an animal model.
Similar news · Read more »
- Human C-reactive protein regulates myeloma tumor cell growth and survival
09-10-2007 · EurekAlert!
Scientists report that a protein best known as a common marker of inflammation plays a key role in the progression of human cancer. The research, published by Cell Press in the September issue of the journal Cancer Cell, implicates C-reactive protein (CRP) as a potential target for cancer treatment.
Similar news · Read more »
- Study reveals improved prediction of prostrate cancer
01-30-2008 · EurekAlert!
Scientists are another step closer to understanding why some people suffer from life-threatening diseases such as cancer. Research published in the new online open access journal BMC Medical Genomics reveals a model that may enable more accurate prediction of the risk of prostate cancer progression. By combining the Gleason score (a pathological score given to prostate cancer based on its microscopic appearance) with structured data from biomarker assessments, the researchers have developed a model for predicting the likelihood of prostate cancer virulence.
Similar news · Read more »
- Jefferson scientists find blood vessel-building protein halts blood vessels from forming in cancer
11-14-2006 · EurekAlert!
A piece of the protein cellular scaffolding involved in building blood vessels duringdevelopment might have the opposite effect in tumors. Scientists have found that the protein fragment endorepellin blocks both skin and lung cancer tumors from progressing in animal models by preventing their ability to recruit new blood vessels, a process called angiogenesis. The researchers believe the finding could lead to a new type of tumor inhibitor to prevent cancer from spreading.
Similar news · Read more »
- New 'knock-out' gene model provides molecular clues to breast cancer
09-05-2007 · EurekAlert!
New insights into the role of estrogen receptor in mammary gland development may help scientists better understand the molecular origin of breast cancer, according to new research from the University of Cincinnati.
Similar news · Read more »
- Jefferson scientists show gene reverts cancer genes to normal, predicts breast cancer prognosis
10-31-2006 · EurekAlert!
Scientists have shown that the activity of a gene that commandeers other cancer-causing genes, returning them to normal, can predict the prognosis of an individual with breast cancer. They looked at cancer cells from more than 2,000 breast cancer patients and found that this commandeering or "organizing" ability is increasingly lost in cancer cells and associated with the progression of disease. The more the gene is expressed in breast cancer, the better the patient did.
Similar news · Read more »
- Treatment-induced growth factor causes cancer progression
04-05-2007 · EurekAlert!
A research team at the Vanderbilt-Ingram Cancer Center, led by Carlos Arteaga, M.D., reports in the May issue of the Journal of Clinical Investigation that radiation and chemotherapy increase circulating levels of the growth factor TGF-beta, circulating cancer cells, and tumor metastases in a mouse model of metastatic breast cancer.
Similar news · Read more »
- Purdue research finds similarities in dog, human breast cancer pre-malignant lesions
11-15-2007 · EurekAlert!
Pre-malignant mammary lesions in dogs and humans display many of the same characteristics, a discovery that could lead to better understanding of breast cancer progression and prevention for people and pets, said a Purdue University scientist from the School of Veterinary Medicine.
Similar news · Read more »
- Study offers innovative profile of enzyme that aids tumor growth
10-20-2006 · EurekAlert!
Using an innovative profiling strategy, scientists at the Scripps Research Institute have characterized an enzyme that is "highly elevated" in aggressive human tumor cells. When the enzyme, KIAA1363, was inactivated, it impaired tumor growth and migration in both ovarian and breast cancer cells, suggesting that inhibitors of this enzyme may prove valuable in the treatment of multiple types of cancer.
Similar news · Read more »
- Jefferson scientists identify protein key to breast cancer spread, potential new drug target
04-09-2007 · EurekAlert!
Researchers at the Kimmel Cancer Center at Jefferson have identified a protein that they say is key to helping a quarter of all breast cancers spread. The finding, reported online the week of April 9, 2007, in the journal Proceedings of the National Academy of Sciences, could be a potential target for new drugs aimed at stopping or slowing the growth and progression of breast cancer.
Similar news · Read more »
