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Postmenopausal hormone therapy and coronary disease -- the truth of the matter

The results of WHI-CACS, now published in New England Journal of Medicine are very encouraging, since women who were randomized to the estrogen arm of the WHI had significantly smaller calcification scores than counterparts in the placebo arm. This study reaffirms that estrogen has a wide range of well-documented beneficial metabolic and vascular effects, provided that treatment is started early in menopause. Women can be reassured that estrogen therapy is cardioprotective at least until age 65.

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Keywords: postmenopausal, hormone, therapy, coronary, disease, truth, matter

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Similar news on "Postmenopausal hormone therapy and coronary disease -- the truth of the matter":

1. Effect of hormone therapy on risk of heart disease may vary by age and years since menopause
   04-03-2007 · EurekAlert!
   Secondary analyses of findings from the Women's Health Initiative suggest that women who begin hormone therapy within 10 years of menopause may have less risk of coronary heart disease (CHD) due to hormone therapy than women farther from menopause. Overall, hormone therapy did not reduce the risk of CHD.
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2. Timing of start of hormone therapy may have effect on risk of coronary heart disease
   04-03-2007 · EurekAlert!
   Women who initiate hormone therapy closer to menopause tend to have a reduced risk of coronary heart disease compared to women who begin treatment further from menopause, but researchers did not find this reduced risk was statistically significant, according to a study in the April 4 issue of JAMA.
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3. 1 in 5 early-stage breast cancer patients may not follow hormonal therapy plan
   12-16-2006 · EurekAlert!
   Postmenopausal women with early-stage, hormone-sensitive breast cancer have a lower risk of disease recurrence when their treatment includes a new class of hormone therapy drugs, yet one out five women prescribed the drugs may not take them regularly.
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4. Weight gain related to postmenopausal breast cancer risk
   10-22-2007 · EurekAlert!
   Women who gain weight throughout adulthood rather than maintaining a stable weight may have an increased risk for breast cancer, according to a report in the Oct. 22 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. This finding was observed among women who did not take hormone therapy after menopause.
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5. High blood pressure during pregnancy may lead to postmenopausal heart disease
   02-05-2007 · EurekAlert!
   Women who develop high blood pressure during pregnancy are more likely to develop increased coronary calcification later in life than those who maintained a normal blood pressure.
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6. Colon cancer a disease of hormone deficiency, Jefferson team finds
   08-01-2007 · EurekAlert!
   Researchers have found new evidence suggesting that colon cancer is a disease of missing hormones that could potentially be treated by hormone replacement therapy.Early in colon cancer development, two intestinal cell growth-controlling hormones are "lost," disrupting the activity of the hormones' receptor, GCC. Using two mouse models of colon cancer development in people, the scientists showed that GCC signaling blocks tumors from forming, meaning that colon cancer could be a disease of hormone insufficiency.
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7. IMS updated recommendations on postmenopausal hormone therapy
   05-16-2007 · EurekAlert!
   The Updated Recommendations express the views of the International Menopause Society on the principles of hormone therapy in the peri- and postmenopausal periods. New data and re-analyses of older studies by women's age show that, for most women, the potential benefits of hormone therapy given for a clear indication are many and the risks are few when initiated within a few years of menopause.
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8. Estrogen use before 65 linked to reduced risk of Alzheimer's disease
   05-02-2007 · EurekAlert!
   Women who use hormone therapy before the age of 65 could cut their risk of developing Alzheimer's disease or dementia. This possibility is raised by research that will be presented at the American Academy of Neurology's 59th Annual Meeting in Boston, April 28-May 5, 2007.
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9. Reducing cardiovascular disease risk factors when discontinuing hormone replacement therapy
   05-15-2007 · EurekAlert!
   Hormone replacement therapy (HRT) can reduce many cardiovascular disease (CVD) risks, but many women have stopped using HRT due to reports that HRT may increase the risk of breast cancer and heart disease. In a study published in the June issue of the American Journal of Preventive Medicine, researchers from the University of Pittsburgh Graduate School of Public Health examined whether the increased CVD risk from stopping HRT could be minimized by lifestyle change intervention.
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10. Hormone drug type makes survival difference in advanced breast cancer
    01-30-2007 · EurekAlert!
    Aromatase inhibitors, a type of hormone therapy used to treat advanced breast cancer in postmenopausal women, result in a small but significant increase in overall survival when compared to other hormone treatments, according to a new systematic review of studies.
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