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Marker predicts pancreatic cancer outcome after surgery, Jefferson surgeon finds
06-22-2007 · EurekAlert!A team of researchers, led by surgeons at the Kimmel Cancer Center at Jefferson in Philadelphia, has found further evidence supporting the ability of a protein to predict how well a patient with advanced pancreatic cancer will do after surgery, chemotherapy and radiation.
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Keywords: marker, predicts, pancreatic, cancer, outcome, surgery, jefferson, surgeon, predict
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- Jefferson scientists show gene reverts cancer genes to normal, predicts breast cancer prognosis
10-31-2006 · EurekAlert!
Scientists have shown that the activity of a gene that commandeers other cancer-causing genes, returning them to normal, can predict the prognosis of an individual with breast cancer. They looked at cancer cells from more than 2,000 breast cancer patients and found that this commandeering or "organizing" ability is increasingly lost in cancer cells and associated with the progression of disease. The more the gene is expressed in breast cancer, the better the patient did.
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- Jefferson pharmacologist says biomarker discovery bodes well for better cancer diagnostics
05-01-2007 · EurekAlert!
A pharmacologist at the Kimmel Cancer Center at Jefferson says that new findings suggesting a genetic marker can help distinguish between chronic pancreatitis and pancreatic cancer and gauge who will do well with cancer treatment have important implications for improved cancer diagnostics and tumor profiling. In an editorial he co-authored May 2 in JAMA, Scott Waldman, M.D., Ph.D., says that researchers at Ohio State University have identified "a new level of biological regulation."
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- Outcome of prostate cancer surgery depends on the experience of the surgeon
07-24-2007 · EurekAlert!
According to a new study published online today in the Journal of the National Cancer Institute, prostate cancer patients treated by highly experienced surgeons are much more likely to be cancer-free five years after surgery than patients treated by surgeons with less experience.
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- Molecular marker may help identify pancreatic cancer, and possibly predict survival time
05-01-2007 · EurekAlert!
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- Jefferson scientists find protein may be key in developing deadly form of pancreatic cancer
10-11-2007 · EurekAlert!
A tumor-blocking protein previously implicated in prostate and breast cancer development may also be behind the most aggressive type of pancreatic cancer. Researchers have discovered that the protein pp32 -- which normally applies the brakes on a cancer-causing gene -- is missing in an aggressive form of pancreatic cancer. Though the work is preliminary, the scientists say, the absent protein could eventually become a marker for the disease and a potential drug target.
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- Jefferson scientists uncover role of cancer stem cell marker: controlling gene expression
01-17-2008 · EurekAlert!
Scientists at Jefferson's Kimmel Cancer Center in Philadelphia have made an extraordinary advance in the understanding of the function of a gene previously shown to be part of an 11-gene "signature" that can predict which tumors will be aggressive and likely to spread. The gene, USP22, encodes an enzyme that appears to be crucial for controlling large scale changes in gene expression, one of the hallmarks of cancer cells.
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- Pancreatic surgery riskier for obese patients
06-04-2007 · EurekAlert!
Obesity may contribute to a greater likelihood of post-operative complications for patients having pancreatic surgery, a surgeon at Thomas Jefferson University Hospital has found. A study of 202 pancreatic surgeries from 2000 to 2005 indicates obese patients had an increased time on the operating table, blood loss, length of hospital stay and rate of serious complications compared to normal weight individuals.
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- Breast cancer susceptibility gene predicts outcome and response to treatment in lung cancer
09-25-2007 · EurekAlert!
Researchers have found that the breast cancer susceptibility gene, BRCA1, plays a significant role in nonsmall cell lung cancer. They told the European Cancer Conference in Barcelona that not only can it be used to predict outcome for patients with NSCLC, but it may also prove to be a valuable tool in choosing the best therapy for them.
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- New biomarker test could predict outcome for bladder cancer patients
02-01-2007 · UT Southwestern Medical Center
A set of molecular biomarkers might better predict the recurrence of bladder cancer than conventional prognostic features such as the stage or grade of the malignancy at the time it is discovered, UT Southwestern Medical Center researchers have found.
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