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Disease outbreak detection, retinal gene therapy

In this issue: An epidemiological network model for disease outbreak detection, and Canine and human visual cortex intact and responsive despite early retinal blindness from RPE65 mutation.

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Keywords: disease, outbreak, detection, retinal, gene, therapy

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Similar news on "Disease outbreak detection, retinal gene therapy":

1. Reprogrammed human adult stem cells rescue diseased muscle in mice
   12-12-2007 · EurekAlert!
   Scientists report that adult stem cells isolated from humans with muscular dystrophy can be genetically corrected and used to induce functional improvement when transplanted into a mouse model of the disease. The research, published by Cell Press in the December issue of Cell Stem Cell, represents a significant advance toward the future development of a gene therapy that uses a patient's own cells to treat this devastating muscle-wasting disease.
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2. Rush and UCSF found gene therapy appeared to reduce symptoms of Parkinson's by 40%
   10-16-2006 · EurekAlert!
   Ceregene, Inc., announced today that CERE-120, a gene therapy product in development for the treatment of Parkinson's disease, was well tolerated and appeared to reduce symptoms by approximately 40%.
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3. Gene therapy for blindness clears hurdle in mice
   03-14-2007 · EurekAlert!
   University of Florida Genetics Institute researchers were able to use interfering RNA in experiments with mice to quiet a gene that plays a crucial role in a leading cause of inherited blindness. Disabling the gene is a step toward developing a gene therapy to treat people with retinitis pigmentosa, an inherited disease that attacks the light-sensing cells in the eye.
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4. Penn researchers report that gene therapy awakens the brain despite blindness from birth
   06-25-2007 · EurekAlert!
   Researchers at the University of Pennsylvania have demonstrated that gene therapy used to restore retinal activity to the blind also restores function to the brain's visual center, a critical component of seeing.
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5. Vaxfectin-formulated measles DNA vaccine elicits long-term protection in nonhuman primates
   05-31-2007 · EurekAlert!
   Diane Griffin, M.D., Ph.D., of Johns Hopkins University Bloomberg School of Public Health will be presenting findings on Thursday, May 31 at the 10th Annual American Society of Gene Therapy meeting in Seattle showing that an experimental measles DNA vaccine showed promising results in infant monkeys and achieved "sterilizing immunity," or near-complete eradication of disease, in juvenile monkeys. The studies were conducted under a grant from the Bill and Melinda Gates Foundation.
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6. Under magnetic force, nanoparticles may deliver gene therapy
   07-31-2007 · EurekAlert!
   After binding DNA segments to tiny iron-containing spheres called nanoparticles, researchers have used magnetic fields to direct the nanoparticles into arterial muscle cells, where the DNA could have a therapeutic effect. Although the research, done in cell cultures, is in early stages, it may represent a new method for delivering gene therapy to benefit blood vessels damaged by arterial disease.
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7. Light-sensitive photoswitches could restore sight to those with macular degeneration
   10-31-2006 · EurekAlert!
   The major cause of blindness in this country is the death of photoreceptors -- rods and cones -- in the retina, a disease called macular degeneration. A possible new therapy involves inserting photoswitches into surviving retinal cells, giving them the gift of sight. NIH's nanomedicine initiative just awarded UC Berkeley and Lawrence Berkekley National Laboratory scientists $6 million to pursue this technique in mice.
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8. Research team enlightens the reasons for severe blindness
   08-06-2007 · EurekAlert!
   Coordinated by the geneticist Ronald Roepman from Nijemegen, an important step has now been made in this direction by an international research team with the participation of the GSF-National Research Center for Environment and Health: They identified a further gene for the inherited retinal disease Leber Congenital Amaurosis and discovered first evidences how it functions.
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9. Batten down the hatches against HIV
   02-20-2007 · EurekAlert!
   A promising approach to gene therapy involves short DNA fragments (interfering RNA) that bind to specific genes and block their "translation" into the corresponding, disease-related protein. A stumbling block has been the efficient and targeted delivery of RNA into the cells. Researchers led by Hongjie Dai at Stanford University have sucessfully used carbon nanotubes as a "means of transport," they write in "Angewandte Chemie."
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10. New software to aid early detection of infectious disease outbreaks
    12-06-2007 · EurekAlert!
    A newly released software program will let health authorities at the site of an infectious disease outbreak quickly analyze data, speeding the detection of new cases and the implementation of effective interventions.
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