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Frog molecule could provide drug treatment for brain tumors

A synthetic version of a molecule found in the egg cells of the Northern Leopard frog (Rana pipiens) could provide the world with the first drug treatment for brain tumors.

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Keywords: frog, molecule, provide, drug, treatment, brain, tumors, tumor

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1. Frog molecule could provide drug treatment for brain tumours
   06-26-2007 · University of Bath
   A synthetic version of a molecule found in the egg cells of the Northern Leopard frog (Rana pipiens) could provide the world with the first drug treatment for brain tumours.
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2. Therapeutic unshackles p53 and causes tumor regression
   03-15-2007 · EurekAlert!
   Infection with Kaposi's sarcoma virus (KSHV) can cause 3 types of tumor, including primary effusion lymphoma (PEL). Although KSHV has been known to cause tumors for many years, there are no effective therapies for KSHV-induced tumors. In a new study it is shown that the small-molecule inhibitor Nutlin-3a has antitumor effects in a mouse xenograft model of PEL, indicating that it might provide a viable therapeutic option for the treatment of individuals with PEL.
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3. Treatment capitalizes on unique qualities of radioisotope to prolong lives of brain tumor patients
   01-30-2008 · EurekAlert!
   In a study to determine safe dosages of the isotope astatine-211 for patients with recurring brain tumors, researchers were pleasantly surprised to find that not only was the isotope's potency sufficient to kill residual cancer cells without damaging sensitive healthy brain cells, but the patients experienced longer survival rates.
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4. Blood-vessel blocker aids cancer-killing virus
   11-27-2007 · EurekAlert!
   Cancer-killing viruses are a promising therapy for incurable brain tumors, but their effectiveness has been limited in part because immune cells rapidly eliminate them. That immune response might be slowed, and the virus given more time to kill cancer cells, by blocking the growth of blood vessels in the tumor, new Ohio State research suggests. The study indicates that pretreatment with a drug that blocks blood-vessel growth might improve the effectiveness of cancer-killing viruses.
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5. Research could lead to treatment for Alzheimer's disease
   04-17-2007 · EurekAlert!
   A molecule designed by a Purdue University researcher could lead to the first drug treatment for Alzheimer's disease. There are many people suffering, and no effective treatment is available to them. The new molecule prevents the first step in a chain of events that leads to amyloid plaque formation in the brain.
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6. Scripps research combination therapy obliterates new vessel growth in tumors and retinopathy
   01-09-2007 · EurekAlert!
   Using a new and dramatically effective treatment approach, scientists at the Scripps Research Institute have for the first time achieved complete inhibition of new blood vessel growth in animal models of a highly vascular brain tumor and of neovascular eye diseases with little or no effect on normal tissue vasculature.
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7. Gene profiling predicts resistance to breast cancer drug Herceptin
   02-20-2007 · EurekAlert!
   Using gene chips to profile tumors before treatment, researchers at Harvard and Yale Universities found markers that identified breast cancer subtypes resistant to Herceptin, the primary treatment for HER2-positive breast cancer. They say this advance could help further refine therapy for the 25 to 30 percent of breast cancer patients with this class of tumor.
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8. Research suggests new treatment suitable for all patients
   01-01-2008 · EurekAlert!
   New research at Wake Forest University Baptist Medical Center suggests that a three-drug cocktail may one day improve outcomes in patients with glioblastoma multiforme, a type of brain tumor with a dismal prognosis. Two of the drug candidates have been developed, and the team is working on the third -- all targeted to kill or impair cancer cells and spare healthy brain.
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9. 2 microRNAs promote spread of tumor cells
   01-28-2008 · EurekAlert!
   Scientists at The Wistar Institute and their colleagues have identified two microRNAs that promote tumors' deadly spread. One of the miRNAs may provide an early warning of metastatic breast cancer and the need for aggressive treatment. In a study to be published Feb. 1 in Nature Cell Biology that is available online, the researchers describe how two miRNAs transformed non-invasive human breast cancer cells into cells that rapidly metastasized in cell cultures and mice.
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10. Drug combination might offer hope for patients deadly brain tumors
    10-18-2007 · EurekAlert!
    Brain cancer patients with the poorest prognosis -- those with a type of deadly tumor known as glioblastoma multiforme -- may survive longer with a drug that chokes off a tumor's blood supply.
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