Daily non-political popular news in brief.
The Journal of Clinical Pharmacology looks at effects of smoking cessation drug, 'Varenicline'
10-31-2006 · EurekAlert!Smoking is the world's leading cause of premature death. Smokers who quit are able to significantly reduce their risk of premature death and other health issues -- almost completely if they quit by age thirty and by fifty percent if they quit after age fifty. Because it's so difficult to quit smoking, many are turning to smoking cessation drugs, such as varenicline, to help minimize cravings and other withdrawal symptoms.
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Keywords: journal, clinical, pharmacology, looks, effects, smoking, cessation, drug, varenicline, look, effect
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- The Journal of Clinical Pharmacology looks at effects of smoking cessation drug, varenicline
10-31-2006 · EurekAlert!
Smoking is the world's leading cause of premature death. Smokers who quit are able to significantly reduce their risk of premature death and other health issues -- almost completely if they quit by age thirty and by fifty percent if they quit after age fifty. Because it's so difficult to quit smoking, many are turning to smoking cessation drugs, such as varenicline, to help minimize cravings and other withdrawal symptoms.
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- Study found no drug interference with pomegranate juice
08-20-2007 · EurekAlert!
A study published in the Journal of Clinical Pharmacology finds that pomegranate juice does not interact with medication. Earlier studies suggested that, like grapefruit juice, pomegranate juice may interfere with metabolism of drugs by inhibiting CYP3A, an enzyme that allows the body to transform and eliminate a drug. This is the first study using human subjects to test the drug interactions of pomegranate juice, unlike prior studies which were conducted in vitro and in animals.
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- Phone-based therapy eases depression long term
03-22-2007 · EurekAlert!
When people receive brief telephone-based psychotherapy soon after starting antidepressant medication, strong positive effects may continue 18 months after their first session. So concludes a Group Health study in the April Journal of Consulting and Clinical Psychology. With close to 400 patients, this is the largest study yet of psychotherapy delivered by phone. It’s also the first to study the effectiveness of combining phone-based therapy with antidepressant drug treatment as provided in everyday medical practice.
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- Story ideas from the Journal of Biological Chemistry
01-14-2008 · EurekAlert!
COX-2 inhibitors like Celecoxib have come under scrutiny lately due to adverse cardiovascular side-effects stemming from COX-2 reduction. In both fruit fly and rat models, researchers reveal another adverse effect of Celecoxib; this drug can induce arrhythmia. More interestingly, this effect is independent of the COX-2 enzyme.
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- Anemia treatment may be a double-edged sword
01-30-2008 · EurekAlert!
A study in February's Journal of Clinical Investigation finds that erythropoietin, commonly given for anemia, promotes blood-vessel growth in the eye, an effect that could either improve/worsen disease for patients with cancer, diabetic retinopathy, or retinopathy of prematurity. The effects on retinopathy depend on the timing of when erythropoietin is given.
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- Drug's potential adverse side effect explained
09-06-2007 · EurekAlert!
Drugs that are agonists of the receptor PPAR-gamma are used to treat individuals with diabetes. However, it has been suggested that their use is associated with a slightly increased risk of heart failure. A potential explanation for this adverse effect that is observed in a minority of patients is outlined in a new study in the Journal of Clinical Investigation.
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- Kaiser Permanente -- Group Health study shows depression worsens HIV treatment
12-20-2007 · EurekAlert!
The largest study to examine the effect of depression on HIV treatment appears in the online edition of the Journal of Acquired Immune Deficiency Syndromes. The study by Kaiser Permanente and Group Health found depression significantly worsens a patient's adherence to highly active antiretroviral therapy and clinical measures but that effective antidepressant medication reverses this outcome. The study looked at 3,359 HIV-infected patients to measure the effects of depression -- with and without SSRIs.
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- Pine tree bark reduces side effects in hypertensive patients
11-15-2006 · EurekAlert!
A study published in the October journal of Clinical and Applied Thrombosis/Hemostasis shows Pycnogenol (pic-noj-en-all), an antioxidant plant extract from the bark of the French maritime pine tree reduced edema, a typical side effect of antihypertensive medications, by 36 percent in patients taking these medications.
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- Researchers propose reason for severe side-effects of Northwick Park clinical trial
01-25-2007 · EurekAlert!
A possible reason why the Northwick Park clinical trial of the drug TGN1412 in the UK caused multiple organ failure in human volunteers is revealed in research presented today at a conference near Paris. The research shows that stimulating the molecule CD28 on cells that mediate the immune response, known as T cells, can have an adverse effect if these immune cells have been activated and altered by infection or illness in the past.
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- Heavy smoking cuts women's chance of pregnancy -- even with donated oocytes
11-08-2006 · EurekAlert!
Heavy smoking may reduce female fertility by directly affecting the uterus -- making it less receptive and reducing the chances the embryo will implant, according to research published on line (Thursday 9 November) in Europe's leading reproductive medicine journal Human Reproduction. This is true even if the woman is undergoing IVF with donated oocytes, demonstrating that tobacco damages the uterine lining independently of the (already known) effects of tobacco on the ovaries.
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