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Method to prevent hemorrhagic complications of thrombolytic therapy of blood clots is discovered

The now reported study led by Dr. Perttu J. Lindsberg from the Helsinki University Central Hospital investigated thrombolytics-related brain hemorrhage formation in an experimental stroke model in rats. It found that, in addition to the clot lysing effect, the drug used for this purpose, alteplase (recombinant tissue plasminogen activator) also possesses proinflammatory properties and activates and degranulates mast cells, a kind of tissue-based immune cell.

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Keywords: method, prevent, hemorrhagic, complications, thrombolytic, therapy, blood, clots, discovered, complication, clot

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