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Team sheds light on cells' career path
07-01-2007 · Massachusetts Institute of Technology (MIT)How do cells specialize, despite having exactly the same DNA? Scientists at the Broad Institute have unveiled a special code, within the "chromatin" proteins surrounding the cell's DNA, that could unlock the mysterious choices underlying cell identity.
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Keywords: team, sheds, light, cells, career, path, shed, cell
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- Tissue geometry plays crucial role in breast cell invasion
10-12-2006 · EurekAlert!
Researchers with the U.S. Department of Energy's Lawrence Berkeley National Laboratory have created a first-of-its-kind model for studying how breast tissue is shaped and structured during development. The model may shed new light on how the misbehavior of only a few cells can facilitate metastatic invasion because it shows that the development of breast tissue, normal or abnormal, is controlled not only by genetics, but also by geometry.
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- Discredited Korean embryonic stem cells' true origins revealed
08-02-2007 · EurekAlert!
A report from researchers at Children's Hospital Boston and the Harvard Stem Cell Institute sheds new light on a now-discredited Korean embryonic stem cell line, setting the historical record straight and also establishing a much-needed set of standards for characterizing human embryonic stem cells. The report was published online Aug. 2 by the journal Cell Stem Cell.
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- Scripps Research scientists shed new light on how antibodies fight HIV
09-06-2007 · EurekAlert!
Leading an international team of scientists, immunologists at the Scripps Research Institute have uncovered the first evidence that an HIV antibody is most effective when it binds not only to the virus, but also to host immune cells. The findings suggest that antibody efficiency depends on both directly neutralizing the virus and activating the host immune response.
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- A unique arrangement for egg cell division
08-09-2007 · EurekAlert!
Using a powerful microscope, researchers from the European Molecular Biology Laboratory have now revealed how the molecular machinery functions that is responsible for chromosome reduction of egg cells in mice. In the current issue of Cell they report the assembly of this machinery, which is very different from what happens in all other cells in the body. The process is likely conserved across species, and the new insights might help shed light on defects occurring in human egg cell development.
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- An AIDS-related virus reveals more ways to cause cancer, Penn researchers find
10-08-2007 · EurekAlert!
Researchers have shed new light on how Kaposi's Sarcoma-associated Herpes Virus subverts normal cell machinery to cause cancer. A KSHV protein called latency-associated nuclear antigen (LANA) helps the virus hide out from the immune system in infected cells. When LANA takes the place of other proteins that control cell growth, it can cause uncontrolled cell replication.
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- Protein-dependent 'switch' regulates intracellular trafficking in epithelial cells
12-11-2007 · EurekAlert!
With findings highlighted on a recent cover of Developmental Cell, researchers at Weill Cornell Medical College in New York City have shed important new light on key trafficking mechanisms within epithelial cells. Epithelial cells line the outside of nearly all organs.
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- Tuberculosis: The bacillus takes refuge in adipose cells
12-20-2006 · EurekAlert!
A team from the Institut Pasteur has recently shown that the tuberculosis bacillus hides from the immune system in its host's fat cells. This formidable pathogen is protected against even the most powerful antibiotics in these cells, in which it may remain dormant for years. This discovery, published in PLoS ONE, sheds new light on possible strategies for fighting tuberculosis. Attempts to eradicate the bacillus entirely from infected individuals should take these newly identified reservoir cells into account.
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- How cells keep in shape
12-02-2007 · EurekAlert!
Researchers at the European Molecular Biology Laboratory and the Institute for Atomic and Molecular Physics, the Netherlands, have now decoded a molecular mechanism that plays an important role in the development of a cell's shape. In this week's issue of Nature they report a new experimental approach that sheds light on the interaction between proteins and the cell's skeleton.
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- Researchers shed light on shrinking of chromosomes
06-11-2007 · EurekAlert!
Now researchers from the European Molecular Biology Laboratory for the first time tracked chromosome condensation in mammalian cells over the entire course of cell division. In this week's advanced online publication of Nature Cell Biology they report crucial new insights into timing, function and molecular basis of chromosome condensation.
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- Solar cells can take the heat
01-09-2008 · EurekAlert!
Michael Grдtzel and his a team of researchers at the Ecole Polytechnique Federale de Lausanne in Switzerland have fabricated a solvent-free dye-sensitized solar cell based on a binary ionic liquid electrolyte. These devices show a light-conversion efficiency of 7.6 percent under simulated sunlight conditions, which sets a new record for a solvent-free device.
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