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Tick-related disease thrives on cholesterol, study suggests
07-02-2007 · EurekAlert!People who have high cholesterol levels may be much more susceptible to a particular disease transmitted by the bites of ticks, a new study in mice suggests. Scientists infected mice with the bacterium that causes human granulocytic anaplasmosis, a disease with flu-like symptoms. Bacteria levels were 10 times greater in mice that were genetically predisposed to high cholesterol levels and that were also fed a high-cholesterol diet.
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- People at genetic risk for Alzheimer's age mentally just like noncarriers
01-07-2007 · EurekAlert!
Australian researchers say that a genotype that heightens the risk for Alzheimer's disease does not contribute to cognitive change during most of adulthood. The largest study of its kind has found that carriers and noncarriers show the same type and extent of normal age-related cognitive declines, decades before carriers start to more often develop symptoms of dementia. The findings suggest that the higher-risk genotype acts only in later years to layer disease on top of normal aging.
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- Targeting tau: Inflammation study suggests new approach for fighting Alzheimer's
02-01-2007 · EurekAlert!
Researchers at the University of Pennsylvania School of Medicine have shown that impaired function and loss of synapses in the hippocampus of a mouse form of Alzheimer's disease (AD) is related to the activation of immune cells called microglia, which cause inflammation. These events precede the formation of tangles -- twisted fibers of tau protein that build up inside nerve cells -- a hallmark of advanced AD.
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- Green tea extract protects against brain damage in new mouse model of HIV-related dementia
05-01-2007 · EurekAlert!
A green tea extract may represent a new and natural compound for preventing and treating HIV-associated dementia, a study using a new mouse model for the devastating disease suggests.
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- Simvastatin -- For hearts and minds?
07-18-2007 · EurekAlert!
Statins are not all equal when it comes to their potential to guard against dementia, according to a study published in the online open access journal BMC Medicine. Statins are cholesterol-lowering drugs used by heart disease sufferers. The new findings suggest that simvastatin is associated with a lower incidence of dementia and Parkinson's disease. Disagreement over whether statins could guard against these conditions has meant the benefits to dementia sufferers to date have been unclear.
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- Preclinical study suggests organ-transplant drug may aid in lupus fight
08-15-2007 · UT Southwestern Medical Center
A compound related to a drug used in humans to prevent organ-transplant rejection attacks a key biochemical process in the faulty immune cells of lupus-prone mice, suggesting a possible new approach to combating the disease, UT Southwestern Medical Center researchers have found.
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- Ecologists uncover links between fever and living fast, dying young
10-29-2007 · EurekAlert!
Fever is an effective defence against disease, but new research suggests that not all animals use it when exposed to infection. The study, published online in the British Ecological Society's journal Functional Ecology, found large differences in fever responses among closely related species of mice and suggests that an animal's reproductive strategy could explain some of this intriguing variation.
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- Exercise can cut coronary artery disease risk for some with MS
04-30-2007 · EurekAlert!
Results of a new study suggest that people with mild to moderate MS are capable of improving their aerobic fitness levels similar to their non-MS counterparts. While physical inactivity may predispose MS patients to have increased coronary artery disease risk, MS-related symptoms don't preclude this group from potentially reducing their risk factors through exercise.
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- 'Diabetes gene' may be linked to polycystic ovary syndrome
12-06-2006 · EurekAlert!
A study of polycystic ovary syndrome (PCOS) provides further evidence that calpain-10, the "diabetes gene," is related to PCOS susceptibility. PCOS affects up to five percent of the female population, and those diagnosed with the disease have a 2- to 7-fold risk of developing type 2 diabetes mellitus. The data suggest that one area of the gene, the SNP ins/del-19, may be related to both PCOS and type 2 diabetes.
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- NHLBI media availability: Overweight girls at risk for cardiovascular disease
01-08-2007 · EurekAlert!
Results from the NHLBI Growth and Health Study of more than 2,300 girls suggest that girls as young as age 9 who are overweight are at increased risk for short-term and long-term problems that increase the chances of developing cardiovascular disease. Those who were overweight were more likely to have elevated blood pressure and cholesterol levels compared to girls who were not overweight. The study also provides insight into differences between African-American and Caucasian girls.
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- Health disparities in prostate cancer stem from lack of care, not lack of knowledge
03-12-2007 · EurekAlert!
Decreasing the rates of prostate cancer among black men may require improving access to routine health care, rather than increased education about the disease, a study from the University of North Carolina at Chapel Hill School of Medicine suggests.
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