Daily non-political popular news in brief.

Gene variations directly link inflammation to an increased risk for lung cancer

Variations in two genes related to inflammation may be a major risk factor for developing lung cancer, according to a team of scientists from the National Cancer Institute and the University of Texas M. D. Anderson Cancer Center. The effect of these genes is especially strong among heavy smokers, suggesting that the inflammatory response is important in modulating the damage caused by tobacco smoke.

Read more »

Keywords: gene, variations, directly, link, inflammation, increased, risk, lung, cancer, variation

« Previous | Next »

Similar news on "Gene variations directly link inflammation to an increased risk for lung cancer":

1. Possible genetic link to schizophrenia identified
   02-08-2007 · EurekAlert!
   Several neurological and psychiatric disorders, including schizophrenia, are associated with changes in the brain that affect nerves that communicate with each other using dopamine. One protein that is crucial for dopamine-mediated neuronal communication in animals is DARPP-32. Now, researchers have shown that the gene that encodes DARPP-32 in humans exhibits genetic variation and that one particular variant is associated with increased performance in a number of cognitive tests and with an increased risk of schizophrenia.
   Similar news · Read more »
   
2. Other highlights in the Nov. 13 JNCI
   11-13-2007 · EurekAlert!
   Other highlights in the Nov. 13 JNCI include a simple model to predict breast cancer risk, the link between smoking and rectal cancer, research into how a cancer drug causes heart damage, a gene that may inhibit lung cancer, BRCA1's influence on drug response, and the difficulties assigning patients to cancer subtypes.
   Similar news · Read more »
   
3. Vitamin D, variations in its receptor, and prostate cancer
   03-19-2007 · EurekAlert!
   Results of this study by Haojie Li and colleagues suggest that vitamin D deficiency is common among men in the US, and that vitamin D status and genetic variation in the VDR gene affect prostate cancer risk.
   Similar news · Read more »
   
4. Vitamin D, variations in its receptor and prostate cancer
   03-19-2007 · EurekAlert!
   Results of this study by Haojie Li and colleagues suggest that vitamin D deficiency is common among men in the US, and that vitamin D status and genetic variation in the VDR gene affect prostate cancer risk.
   Similar news · Read more »
   
5. Gene variation affects pain sensitivity and risk of chronic pain
   10-22-2006 · EurekAlert!
   A new NIH-funded study shows that a specific gene variant in humans affects both sensitivity to short-term (acute) pain in healthy volunteers and the risk of developing chronic pain after one kind of back surgery. Blocking increased activity of this gene after nerve injury or inflammation in animals prevented development of chronic pain.
   Similar news · Read more »
   
6. Other highlights from the March 21 JNCI
   03-20-2007 · EurekAlert!
   Also in the March 21 JNCI are a study on the link between fat intake and breast cancer risk, a plant compound that may decrease breast cancer risk, a critique of the use of progression-free survival in cancer clinical trials, and a mutation to a mismatch repair gene that is associated with colorectal cancer.
   Similar news · Read more »
   
7. Shields Down: A cancer-fighting gene declines in old age
   10-06-2007 · Science News Online
   Decline of an important anti-cancer gene could contribute to increased cancer risk among the elderly.
   Similar news · Read more »
   
8. 2 heads are better than 1: 2 dysfunctional DNA repair pathways kill tumor cells
   04-12-2007 · EurekAlert!
   Individuals who inherit one mutant copy of any one of about 12 genes that make the proteins of the Fanconi Anemia pathway are at increased risk of developing cancer. This occurs when the remaining "good" copy of the gene becomes mutated in a specific cell type. However, hope of a new treatment for these cancers has now been provided by a new study indicating that inhibiting the protein ATM can kill these cancer cells.
   Similar news · Read more »
   
9. Gene variations point to why lung cancer drugs work better in Japanese vs. US patients
   06-02-2007 · EurekAlert!
   Recent clinical trials revealed that Japanese lung cancer patients survived longer and had a higher rate of side effects than US patients taking the same two drugs, paclitaxel and carboplatin. Now a new study by the Southwest Oncology Group uncovers genetic differences that may explain why. The results, embargoed for release 8:30 a.m. ET Saturday, June 2, are being highlighted at the American Society of Clinical Oncology annual meeting.
   Similar news · Read more »
   
10. Research linking Ashkenazi Jews and breast cancer genes beset by problems
    11-01-2006 · EurekAlert!
    Genetic research over the past decade has linked Ashkenazi Jewish ethnicity to an increased risk for hereditary breast cancer, so much so that certain gene mutations have become known as "Jewish ancestral mutations." But a new study released in the November 2006 issue of the American Journal of Public Health challenges this population-based approach, warning that disparities in access to care and other unintended consequences for specific ethic groups can result, and may have already occurred.
    Similar news · Read more »