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Studies show antidepressants not linked to birth defects
07-03-2007 · EurekAlert!Taking SSRIs, anti-depression drugs, during pregnancy did not significantly increase the overall risk for most birth defects. However, each study found that taking SSRIs during pregnancy was associated with a small increase in the risk of certain rare birth defects -- but they were different birth defects.
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Keywords: studies, show, antidepressants, linked, birth, defects, study, antidepressant, defect
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- Genes linked to suicidal thinking during antidepressant treatment
09-27-2007 · EurekAlert!
Specific variations in two genes have been linked to suicidal thinking that sometimes occurs in people taking the most commonly prescribed class of antidepressants. Depending on the particular mix inherited, these versions increased the likelihood of such thoughts from 2- to 15-fold, a study found. About 1 percent of adult patients were deemed to be at high genetic risk. The findings may hold promise for genetic testing, as more such markers are identified.
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- Women prescribed drugs linked to birth defects not often advised to use birth control
09-17-2007 · EurekAlert!
Although prescription medications that may increase the risk of birth defects are commonly used by women in their childbearing years, only about half receive contraceptive counseling from their health-care providers, according to a large-scale study from the University of Pittsburgh School of Medicine. The study found that one in six women of reproductive age filled a prescription for a medication labeled by the FDA as increasing the risk of fetal abnormalities.
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- First-ever study: lack of critical lubricant causes wear in joints
11-06-2007 · EurekAlert!
For the first time, researchers have linked increased friction with early wear in the joints of animals. Work led by Brown University physician and engineer Gregory Jay, MD, shows mice that do not produce the protein lubricin begin to show wear in their joints less than two weeks after birth. This finding not only points up the protective power of lubricin but also suggests that it could be used to prevent joint wear after an injury.
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- Immunosuppressant further linked to birth defects
02-06-2008 · EurekAlert!
A new study documents malformations seen in an infant born to a kidney transplant recipient who had taken mycophenolate mofetil, a widely used immunosuppressant available commercially as Cellcept.
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- Study examines genetic defects linked to body abnormalities in patients with childhood cancer
01-01-2008 · EurekAlert!
Children with cancer have a higher prevalence of body abnormalities, such as asymmetric lower limbs and curvature of the spine, suggesting that the genetic defect responsible for the abnormality may play a role in the development of cancer, according to a study in the Jan. 2 issue of JAMA.
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- SSRI antidepressants do not pose major birth defect risk
06-27-2007 · EurekAlert!
Researchers from Boston University's Slone Epidemiology Center have found that certain selective serotonin reuptake inhibitors antidepressants do not appear to increase the risk for most kinds of birth defects. The findings, to be published in the June 28 issue of the New England Journal of Medicine, suggest that individual SSRIs may increase the risk for some specific defects, but these are rare and the absolute risks are small.
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- Scientists reveal secrets of Homer's Cyclops to help people with Holoprosencephaly
01-17-2007 · EurekAlert!
Scientists from Cleveland, Ohio, and Paris, France, reached an important milestone in understanding a molecular cause of a rare, but serious birth defect, Holoprosencephaly. In this February's FASEB Journal, researchers explain why and how some fetal brains fail to develop two lobes, as well as why and how the related skull and facial defects occur. Information from this study will enable researchers to pursue better approaches toward detecting, preventing, and treating this serious disorder.
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- Tougher gun show controls in California slash sales of weapons linked to crime
06-11-2007 · EurekAlert!
California has succeeded in drastically reducing anonymous and undocumented gun sales and sales of military-style weapons by introducing tighter controls to gun shows reveals a study in the June issue of Injury Prevention.
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- Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
08-10-2007 · EurekAlert!
Researchers report for the first time that genetic variants in mitochondria -- energy-producing structures harboring DNA that are inherited only from the mother -- are directly linked to metabolic markers for type 2 diabetes. The study, which highlights the role of mitochondrial genome variation in the pathogenesis of common diseases, is published online in Genome Research.
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- Enzyme promotes fat formation
10-11-2007 · EurekAlert!
The enzyme TPPII may contribute to obesity by stimulating the formation of fat cells, suggests a study in EMBO reports this week. The enzyme, TPPII, has previously been linked to making people feel hungry, but Jonathan Graff and colleagues now show that it may be even more deeply involved in causing obesity.
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