Daily non-political popular news in brief.
Researchers identify genetic mutation that may alter tumor cell proliferation
07-04-2007 · EurekAlert!Researchers from Eli Lilly & Company and the Phoenix-based Translational Genomics Research Institute today announced finding a novel recurring mutation of the gene AKT1 in breast, colorectal and ovarian cancers. The altered form of AKT1 appears to cause tumor cell proliferation and may play a role in making cells resistant to certain types of therapies. The findings are reported in an advance online publication of the journal Nature.
Read more »
Keywords: researchers, identify, genetic, mutation, alter, tumor, cell, proliferation, researcher
« Previous | Next »
Similar news on "Researchers identify genetic mutation that may alter tumor cell proliferation":
- Genetic fingerprints identify brain tumors' origins
02-01-2007 · EurekAlert!
Genetic fingerprints that reveal where a brain cell came from remain distinct even after the cell becomes a brain tumor, an international coalition of scientists will report in the Feb. 1 issue of Cancer Research.
Similar news · Read more »
- OHSU Cancer Institute researcher discovers what fuels certain cancer mutation
12-10-2007 · EurekAlert!
An Oregon Health & Science University Cancer Institute researcher has discovered that a particular hormone is responsible for driving a cancer enzyme to cause an often deadly red blood cell cancer. Researchers working with the cancer mutation in the JAK2 enzyme have found that the enzyme is dependent on the hormone TNF-alpha to grow and cause a red blood cell cancer called polycythemia vera, said principal investigator Thomas Bumm, M.D., Ph.D., OHSU Cancer Institute member.
Similar news · Read more »
- Researchers identify new drug targets for cancer
12-28-2006 · EurekAlert!
Solving a 100-year-old genetic puzzle, researchers at the UCSD School of Medicine have determined that the same genetic mechanism that drives tumor growth can also act as a tumor suppressor. Their findings could lead to new drug targets for cancer therapies.
Similar news · Read more »
- Support for chromosomal theory of cancer found in cancers' development of drug resistance
06-27-2007 · EurekAlert!
Most cancer researchers are convinced that cancer results from a handful of genetic mutations that kick a cell into uncontrolled growth. UC Berkeley genetics researcher Peter Duesberg disagrees, and finds support for his "chromosomal" theory of cancer in the development of drug resistance by many cancers. While his theory implies their is no magic bullet against cancer, it does provide ways to detect cancer at an early stage.
Similar news · Read more »
- Novel regulation of the common tumor suppressor PTEN
01-11-2007 · EurekAlert!
PTEN is one of the most commonly mutated tumor suppressor genes. It is an antagonist for many cellular growth, proliferation and survival processes. When mutated or deleted, it causes cancers of the prostate, breast, colon and brain. Researchers led by scientists at Memorial Sloan-Kettering Cancer Center have now identified fundamentally novel regulatory mechanisms of PTEN function. The findings from two related studies are published in the Jan. 12 issue of Cell.
Similar news · Read more »
- Penn researchers identify new combination therapy that promotes cancer cell death
07-16-2007 · EurekAlert!
To test the ability of combined therapy, researchers administered TRAIL, a tumor necrosis factor, and sorafenib, an inhibitor currently used to treat renal cancer, to mice with colon carcinomas. It reduced the size of tumors in mice with few side effects
Similar news · Read more »
- MicroRNA 'sponges' could aid cancer studies
08-12-2007 · Massachusetts Institute of Technology (MIT)
MIT researchers have developed a new way to study the function of microRNA, the tiny strands of genetic material that help regulate a cell's genes. The work could shed light on microRNA's hypothesized role in tumor development.
Similar news · Read more »
- Antibody retards growth and induces death in liver cancer cells
07-11-2007 · EurekAlert!
Researchers from the University of Pittsburgh School of Medicine report a significant new advance in the search for an effective treatment for human liver cancer. Using a newly available monoclonal antibody, they demonstrated dramatic reductions in tumor cell proliferation and survival in human and mouse hepatocellular cancer cell lines. This finding has significant implications not only for the treatment of liver cancer but for a number of different types of cancer.
Similar news · Read more »
- University of Pittsburgh scientists find new contributor to aggressive cancers
06-06-2007 · EurekAlert!
Mutations in the cell adhesion molecule known as integrin alpha 7 (integrin б7) lead to unchecked tumor cell proliferation and a significantly higher incidence in cancer spread, or metastasis, in several cancer cell lines, report researchers at the University of Pittsburgh School of Medicine in a study being published today in the Journal of the National Cancer Institute. These findings suggest that integrin б7 represents an important new target for cancer therapy and prevention.
Similar news · Read more »
- Researchers discover new gene responsible for brittle bone disease
10-19-2006 · EurekAlert!
A team of researchers has identified a new genetic mutation responsible for osteogenesis imperfecta (OI), a condition that makes bones much more likely to break, according to a study published today in the journal Cell. Victims may experience just a few fractures in a lifetime or several hundred beginning before birth. The number of Americans affected is unknown, but estimates range from 20,000 to 50,000.
Similar news · Read more »