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Protein's role in lipid absorption may be important to future weight-loss strategies
07-05-2007 · EurekAlert!Researchers at Washington University School of Medicine in St. Louis have found that a protein absorbs lipids in the upper part of the intestine, and they believe its key role in this process may provide a novel approach for obesity treatment in the future.
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Keywords: protein, role, lipid, absorption, important, future, weight-loss, strategies, weight, loss, strategy
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- Major link in brain-obesity puzzle found
01-29-2007 · EurekAlert!
A single protein in brain cells may act as a linchpin in the body's weight-regulating system, playing a key role in the flurry of signals that govern fat storage, sugar use, energy balance and weight, researchers report. And although it's far too early to say how this protein could be useful in fighting obesity, the finding gives scientists an important system to target in future research and the development of anti-obesity medications.
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- Research finds evidence tropical cyclones have climate-control role
05-31-2007 · EurekAlert!
Purdue University researchers have found evidence that tropical cyclones and hurricanes play an important role in the ocean circulation patterns that transport heat and maintain the climate of North America and Europe. These findings suggest that there is an additional factor to be included in climate models that may change predictions of future climate scenarios.
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- Jefferson scientists find protein helps pancreatic cancer cells evade immune system and spread
01-10-2008 · EurekAlert!
A protein that helps prevent a woman's body from rejecting a fetus may also play an important role in enabling pancreatic cancer cells to evade detection by the immune system, allowing them to spread in the body. Researchers found that the metastatic pancreatic cancer cells in the lymph nodes produce enough of the protein, IDO, to wall-off the immune system's T-cells and recruit cells that suppress the immune response to the tumor.
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- Growth factor signals influence balance between normal growth and cancerous growth
11-09-2006 · EurekAlert!
Too much of a signaling protein called insulin-like growth factor-I (IGF-I) may fan the flames of cancer, while too little of the protein may cause short stature, dementia and osteoporosis. New research investigates how the growth hormone/IGF system is affected by the important tumor suppressor gene p53. This interplay of two signaling pathways reinforces questions about the long-term risks of prescribing growth hormone, while suggesting a future new avenue for cancer therapy.
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- Cold feeling traced to source
12-18-2007 · EurekAlert!
For the first time, neuroscientists have visualized cold fibers -- strands reaching from sensory neurons near the spinal cord to nerve endings in the skin tuned to sense different types of cold. The study confirms the important role of the protein TRMP8 in cold-sensing neurons.
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- 2 genes found to play crucial role in cell survival
02-04-2008 · EurekAlert!
New research suggests that two recently discovered genes are critically important for controlling cell survival during embryonic development. The genes, called E2F7 and E2F8, are members of a family of genes that play a fundamental role in development. Members of this family are also involved in cancers of the breast, bladder, stomach and colon. This animal study showed that complete loss of the two genes causes massive cell death and is lethal in developing embryos.
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- Life savers in the gut
01-09-2008 · EurekAlert!
Researchers from the European Molecular Biology Laboratory have discovered that proteins that regulate the body's iron household play a vital role in making sure enough nutrients and water are absorbed in the intestine. Mice lacking these proteins suffer from weight loss and dehydration, the scientists report in the current issue of Cell Metabolism.
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- Blind mice shed light on human sight loss
11-21-2007 · EurekAlert!
Mutant mice could provide genetic clues to understanding incurable human sight loss resulting from retinal degeneration. Research published in the online open access journal Genome Biology uncovers a role for microRNA in retinal disease, and may point the way to future therapies.
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- Loss of gene leads to protein splicing and buildup of toxic proteins in neurons
09-27-2007 · EurekAlert!
Researchers at Mayo Clinic in Jacksonville have discovered how loss of a gene can lead to accumulation of toxic proteins in the brain, resulting in a common dementia, and they say this mechanism may be important in a number of age-related neurological disorders.
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- Calcium aids protein folding as therapy for enzymes in types of lysosomal storage diseases
02-04-2008 · EurekAlert!
By adapting the protein homeostasis network, altering calcium homeostasis can restore the cell's ability to fold and traffic proteins prone to misfolding, offering a new strategy to ameliorate loss-of-function diseases.
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