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Scientists follow familiar TRAIL to new cancer therapy
07-09-2007 · EurekAlert!A new study identifies a combination therapy that may sensitize human cancer cells to a promising treatment currently being used in clinical trials. The research, published in the July issue of the journal Cancer Cell, published by Cell Press, provides a pharmacological method for enhancing the potency and effectiveness of a tumor necrosis factor death receptor ligand against a variety of human cancers.
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Keywords: scientists, follow, familiar, trail, cancer, therapy, scientist
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- Discovery of widespread tumor growth gene holds promise for effective anti-cancer treatment
09-23-2007 · EurekAlert!
Italian scientists will announce on Monday (Sept. 24) that they have found a new and promising target for anti-tumor therapy in cancer. Professor Saverio Alberti, from the CESI, University of Chieti Foundation, Chieti, will tell the European Cancer Conference that he and his team have found a widespread mechanism for the stimulation of tumor growth in man, and that this is leading to the development of novel diagnostic and therapeutic procedures.
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- Scripps Research study reveals new function of protein kinase pathway in tumor suppression
01-25-2007 · EurekAlert!
Scientists at the Scripps Research Institute have discovered a surprising new function of a well-known signaling pathway that, when activated, can inhibit tumor development. This finding may lead to the development of drugs that can serve as an effective cancer therapy by artificially activating this pathway in cancer cells.
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- New biomarker predicts effectiveness of breast cancer drugs
12-07-2006 · EurekAlert!
University of Cincinnati researchers have identified a new way to predict when anti-estrogen drug therapies are inappropriate for patients with hormone-dependent breast cancer.Scientists say these findings could help physicians more accurately predict which tumors will respond to anti-estrogen therapy and improve long-term survival for breast cancer patients.
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- Breast cancer incidence continues to trend low in 2004; decline supports role of HRT
04-18-2007 · EurekAlert!
An extended analysis of cancer rates reinforces a strong association between use of hormone replacement therapy and increased breast cancer incidence, according to research led by scientists at the University of Texas M. D. Anderson Cancer Center and published in the April 19 issue of the New England Journal of Medicine.
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- Dasatinib, Nilotinib show strong early results as frontline therapy for chronic myelogenous leukemia
12-09-2007 · EurekAlert!
Two drugs approved for use as second line therapy for chronic myelogenous leukemia are showing promising results as frontline therapy for newly diagnosed patients in two clinical trials, research teams led by scientists at the University of Texas M. D. Anderson Cancer Center report at the 49th annual meeting of the American Society of Hematology.
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- Early Phase II results show bosutinib safe, effective for CML
12-11-2007 · EurekAlert!
A new drug for chronic myelogenous leukemia works for patients who have developed resistance to frontline therapy and causes fewer side effects than other medications in its class, a research team led by scientists at the University of Texas M. D. Anderson Cancer Center reports at the 49th annual meeting of the American Society of Hematology.
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- Order of chemotherapy, radiation has no effect on breast cancer survival
10-30-2006 · EurekAlert!
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- Scientists design a PSA-activated protoxin that kills prostate cancer
11-10-2006 · EurekAlert!
Scientists have found a way of using a protein made by prostate cancer to target and kill the cancer cells themselves. In preliminary studies the new therapy affected only the prostate, without causing damage to other healthy tissues, and now it is being tested in a phase I clinical trial, according to research presented at the 18th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Prague on Friday.
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- Colon cancer a disease of hormone deficiency, Jefferson team finds
08-01-2007 · EurekAlert!
Researchers have found new evidence suggesting that colon cancer is a disease of missing hormones that could potentially be treated by hormone replacement therapy.Early in colon cancer development, two intestinal cell growth-controlling hormones are "lost," disrupting the activity of the hormones' receptor, GCC. Using two mouse models of colon cancer development in people, the scientists showed that GCC signaling blocks tumors from forming, meaning that colon cancer could be a disease of hormone insufficiency.
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- Reversing cancer cells to normal cells
04-29-2007 · EurekAlert!
A Northwestern University scientist describes new research that used an innovative experimental approach to provide unique insights into how scientists can change human metastatic melanoma cells back to normal-like skin cells -- by exposing the tumor cells to the embryonic microenvironment of human embryonic stem cells, the zebra fish and the chick embryo.
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