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Natural Anti-viral Enzyme Helps Keep Cancer Cells Alive, Researchers Find
10-06-2006 · ScienceDailyA molecule that cells normally use to fight viruses is also involved in keeping cancer cells alive, researchers at UT Southwestern Medical Center have discovered.
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Keywords: natural, anti-viral, enzyme, keep, cancer, cells, alive, researchers, anti, viral, cell, researcher
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- Enzyme alerts cell's powerful army to repair DNA damage
09-05-2007 · EurekAlert!
Each day cells detect and repair daily assaults to our DNA. University of Michigan researchers have discovered that a well-known enzyme scans genes for damage and alerts the major cancer suppressor protein p53. The finding has implications for treating cancer and neurological diseases.
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- OHSU Cancer Institute researcher discovers what fuels certain cancer mutation
12-10-2007 · EurekAlert!
An Oregon Health & Science University Cancer Institute researcher has discovered that a particular hormone is responsible for driving a cancer enzyme to cause an often deadly red blood cell cancer. Researchers working with the cancer mutation in the JAK2 enzyme have found that the enzyme is dependent on the hormone TNF-alpha to grow and cause a red blood cell cancer called polycythemia vera, said principal investigator Thomas Bumm, M.D., Ph.D., OHSU Cancer Institute member.
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- Pathway links inflammation, angiogenesis and breast cancer
08-09-2007 · EurekAlert!
A well-known inflammatory protein spawns an enzyme that inactivates two tumor-suppressing genes, ultimately triggering production of new blood vessels to nourish breast cancer cells, researchers at the University of Texas M. D. Anderson Cancer Center report in the August edition of the journal Cell.
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- Jefferson scientists find aging gene also protects against prostate cancer development
11-27-2006 · EurekAlert!
Cancer researchers have found that a gene that is involved in regulating aging also blocks prostate cancer cell growth. They have shown that the enzyme SIRT1 can block the growth of treatment-resistant prostate cancer cells that overexpress a mutation for the androgen receptor. The scientists hope the newly found connection will aid in better understanding the development of prostate cancer and lead to new drugs against the disease.
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- Protein found to shield pancreatic cancer cells from self-destruction
03-20-2007 · EurekAlert!
An overexpressed protein protects human pancreatic cancer cells from being forced to devour themselves, removing one of the body's natural defenses against out-of-control cell growth, researchers at The University of Texas M. D. Anderson Cancer Center report in the March issue of Molecular Cancer Research.
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- Researchers develop simple method to create natural drug products
09-04-2007 · EurekAlert!
Until now, only the intricate machinery inside cells could take a mix of enzyme ingredients, blend them together and deliver a natural product with an elaborate chemical structure such as penicillin. Researchers at UC San Diego's Scripps Institution of Oceanography and Skaggs School of Pharmacy and Pharmaceutical Sciences and the University of Arizona have for the first time demonstrated the ability to mimic this process outside of a cell.
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- New algorithm matches any tumor cells to best possible anti-cancer treatments
07-23-2007 · EurekAlert!
An algorithm that could help rapidly sort molecular information about a cancer patient's particular tumor and could help match this information to the right drug treatment would be a breakthrough of enormous value. Two University of Virginia researchers have pioneered just such a system. Using a panel of 60 diverse, human cancer cell lines from the National Cancer Institute (NCI-60), the researchers devised and tested an algorithm designed to match the best potential treatment(s) for a particular tumor in a particular patient.
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- Fetal cell 'transplant' could be a hidden link between childbirth and reduced risk of breast cancer
10-02-2007 · EurekAlert!
Some benefits of motherhood are intangible, but one has been validated through biostatistical research: women who bear children have a reduced risk of developing breast cancer. In Seattle, researchers at the University of Washington and Fred Hutchinson Cancer Research Center believe they have identified a source of this protective effect: fetal cells "transplanted" to the mother before birth.
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- Study proposes new theory of how viruses may contribute to cancer
10-23-2007 · EurekAlert!
A study published in the Oct. 24 issue of PLoS ONE suggests that viruses may contribute to cancer by causing excessive death to normal cells while promoting the growth of surviving cells with cancerous traits. The University of Pittsburgh Cancer Institute researchers suggest that viruses may act as forces of natural selection by wiping out normal cells that support the replication of viruses, leaving behind those cells that have acquired defects in their circuitry.
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- New function for colon cancer gene found
01-17-2008 · EurekAlert!
Dartmouth Medical School geneticists have discovered a striking turnabout role for a gatekeeper known to put on the brakes for colon cancer. Flaws in a gene called adenomatous polyposis coli, which normally prevents excessive cell growth, are thought to trigger development of most colorectal cancers. But in an about face, the tumor suppressor gene also has a second task, the researchers found, as a gas pedal that accelerates signaling between cells.
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