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Neuroscientist comments on stem cell study's success in helping primates with Parkinson's
07-10-2007 · EurekAlert!A University of South Florida neuroscientist reports that the cutting-edge research study of human stem cells in primates with Parkinson's disease is compelling on several fronts -- particularly how the transplanted cells did their job of easing disease symptoms.
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Keywords: neuroscientist, comments, stem, cell, study, success, helping, primates, parkinson, comment, primate
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05-14-2007 · EurekAlert!
UC Irvine neurobiologist Hans Keirstead and his research team today launched a project to develop stem cell lines that genetically match human patients. These lines would allow scientists to better study conditions ranging from diabetes to Parkinson's disease, and they would provide the basis for potential patient-specific stem cell treatments.
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- UCLA scientists produce functioning neurons from human embryonic stem cells
08-07-2007 · EurekAlert!
Scientists with the Institute of Stem Cell Biology and Medicine at UCLA were able to produce from human embryonic stem cells a highly pure, large quantity of functioning neurons that will allow them to create models of and study diseases such as Alzheimer's, Parkinson's, prefrontal dementia and schizophrenia.
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- UF researchers test stem cell therapy for heart patients
10-04-2007 · EurekAlert!
University of Florida doctors treated the first patient in a new study to test whether a person's own stem cells can be used to restore blood flow to the heart by prompting new blood vessels to grow.
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10-10-2007 · EurekAlert!
Researchers have discovered that a key protein controls how stem cells 'choose' to become either skeletal muscle cells that move limbs, or smooth muscle cells that support blood vessels. The results suggest new ways to treat atherosclerosis and cancer, diseases that involve the creation of new blood vessels from stem cell reserves that would otherwise replace worn out skeletal muscle.
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- Replacing the cells lost in Parkinson disease
12-03-2007 · EurekAlert!
Parkinson disease is caused by the progressive degeneration of dopamine brain cells. Replacing these cells is considered a promising therapeutic strategy. Although DA cell-replacement therapy by transplantation of human fetal mesencephalic tissue has shown promise, limited tissue availability means other sources of these cells are needed. A recent study has described one new source for DA cells that provided marked benefit when transplanted into mice with a PD-like disease.
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- Parkinson's approach with stem cells a promising first step
12-01-2006 · EurekAlert!
Brain cells derived from human embryonic stem cells improved the condition of rats with Parkinson's-like symptoms dramatically, but the treatment caused a significant problem -- the appearance of brain tumors -- that scientists are now working to solve. The study is featured on the cover of the November issue of Nature Medicine.
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- Neuron cell stickiness may hold key to evolution of the human brain
11-02-2006 · EurekAlert!
The stickiness of human neurons may have been a key factor in why the human brain evolved beyond the brains of our primate relatives. In a study comparing the genomes of humans, chimpanzees and other vertebrates, researchers at the US Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) and Joint Genome Institute (JGI) found a strikingly high degree of genetic differences in DNA sequences that appear to regulate genes involved in nerve cell adhesion molecules.
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06-06-2007 · EurekAlert!
Researchers at the Abramson Family Cancer Research Institute of the University of Pennsylvania have found that deleting a gene important in embryo development leads to premature aging and loss of stem cell reservoirs in adult mice. This gene, ATR, is essential for the body's response to damaged DNA, and mutations in proteins in the DNA damage response underlie certain types of cancer and other disorders in humans.
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09-04-2007 · EurekAlert!
In the dynamic world of the developing brain, neural stem cells give rise to neurons deep within the brain’s fluid-filled ventricles. These newborn neurons then migrate along the stem cell fibers up to the neocortex, the seat of higher cognitive functions. Now, scientists have discovered a key mechanism of this migration -- one that may also play an important role in other developmental processes and diseases, including cancer.
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- Intensive training post-spinal cord injury can stimulate repair in brain and spinal cord
12-18-2007 · EurekAlert!
Intensive rehabilitation training for patients with spinal cord injuries can stimulate new branches growing from severed nerve fibers, alongside compensatory changes in the brain, say Canadian researchers. Most importantly, it could lead to restoring hand function and the ability to walk.A study recently published in Brain highlights the remarkable benefits of rehabilitation training after cervical spinal cord injury -- something that has been overshadowed in recent years by the promise of cutting-edge stem cell research.
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