Daily non-political popular news in brief.

Cells take risks with their identities

Contrary to textbook models, many genes that should be "off" in embryonic stem cells and specialized adult cells remain primed to produce master regulatory proteins, leaving those cells vulnerable to identity changes. The genes encoding the master regulators of cell fate begin making RNA templates for these proteins, though a control mechanism stops them from finishing the job.

Read more »

Keywords: cells, risks, identities, cell, risk, identity

« Previous | Next »

Similar news on "Cells take risks with their identities":

1. International HIV/AIDS trial finds risks increase on episodic antiretroviral therapy
   11-29-2006 · EurekAlert!
   Results from one of the largest HIV/AIDS treatment trials ever conducted show that a specific strategy of interrupting antiretroviral therapy more than doubles the risk of AIDS or death from any cause. In the study, the investigators used two predetermined levels of CD4+ T cells, the primary immune cell targeted by HIV, to guide them in respectively suspending or restarting the study participants on antiretroviral therapy.
   Similar news · Read more »
   
2. New method for reading DNA sheds light on basis of cell identity
   07-01-2007 · EurekAlert!
   By using a new kind of genomic technology, a new study unveils a special code -- not within DNA, but within the so-called "chromatin" proteins surrounding it -- that could unlock the mysterious developmental choices made by mammalian cells, allowing them to assume roles as diverse as liver cells and neurons.
   Similar news · Read more »
   
3. Long-term cancer risk follows stem cell transplant recipients
   11-27-2006 · EurekAlert!
   Hematopoietic stem cell transplant (HSCT) recipients face a significant long-term risk for developing a second cancer, particularly if they were older at the time of transplant or received stem cells from a female donor, according to a new study.
   Similar news · Read more »
   
4. NOAA: Sunspot is harbinger of new solar cycle, increasing risk for electrical systems
   01-07-2008 · EurekAlert!
   A new 11-year cycle of heightened solar activity, bringing with it increased risks for power grids, critical military, civilian and airline communications, GPS signals and even cell phones and ATM transactions, showed signs it was on its way late Thursday when the cycle's first sunspot appeared in the sun's northern hemisphere, NOAA scientists said.
   Similar news · Read more »
   
5. JCI table of contents: Feb. 1, 2007
   02-01-2007 · EurekAlert!
   This release contains summaries, links to PDFs and contact information for the following newsworthy papers to be published Feb. 1, 2007, in the JCI, including: New role in asthma for old drug; Tumor-reactive T cells boosted by hematopoietic stem cell transplantation; p21 stops HIV-1 in its tracks in hematopoietic stem cells; What makes epithelial cells change their identity?; NOTCHing up heart development; Stress response prevents neurodegeneration, and 4E-BP1 and 4E-BP2 stop mice getting fat.
   Similar news · Read more »
   
6. Team sheds light on cells' career path
   07-01-2007 · Massachusetts Institute of Technology (MIT)
   How do cells specialize, despite having exactly the same DNA? Scientists at the Broad Institute have unveiled a special code, within the "chromatin" proteins surrounding the cell's DNA, that could unlock the mysterious choices underlying cell identity.
   Similar news · Read more »
   
7. New Joslin research identifies sirtuin protein instrumental in fat production and metabolism
   08-15-2007 · EurekAlert!
   A new Joslin Diabetes Center-led study has identified a protein found in fat cells that may play a major role in how fat is produced and stored, offering a new target for treatments to prevent obesity and reduce the risk for type 2 diabetes. This latest research appears in the August 2007 issue of Cell Metabolism.
   Similar news · Read more »
   
8. 'Clumping' protein linked to return of ovarian cancer
   12-15-2006 · EurekAlert!
   Johns Hopkins scientists have discovered that women treated for ovarian cancer are at increased risk of a rapid and potentially fatal recurrence if their tumor cells have high levels of a binding protein that triggers abnormal growth and slows down cell death, both hallmarks of malignancy.
   Similar news · Read more »
   
9. 2 heads are better than 1: 2 dysfunctional DNA repair pathways kill tumor cells
   04-12-2007 · EurekAlert!
   Individuals who inherit one mutant copy of any one of about 12 genes that make the proteins of the Fanconi Anemia pathway are at increased risk of developing cancer. This occurs when the remaining "good" copy of the gene becomes mutated in a specific cell type. However, hope of a new treatment for these cancers has now been provided by a new study indicating that inhibiting the protein ATM can kill these cancer cells.
   Similar news · Read more »
   
10. Protein maintains cross talk between cells that control hair growth
    02-14-2008 · EurekAlert!
    Researchers at Rockefeller University have identified a signaling molecule that is critical for a type of skin cell, called dermal papilla, to ratchet up or clamp down the activity of genes that give them their molecular identity. Without these signals, these skin cells lose their hair-inducing properties -- findings that may provide a new understanding of how stem cells differentiate.
    Similar news · Read more »