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A friendly foe -- Bacteria residing in the gut boost immune response to tumors
07-26-2007 · EurekAlert!Total body irradiation (TBI), which depletes the body of lymphocytes, improves the ability of tumor-specific T cells to cause tumor regression. In a new JCI study researchers show that, in mice, lymphodepletion does not fully account for the tumor regression observed following TBI. They show that disruption of the population of bacteria that normally reside in the gut without causing disease also plays a role in the effectiveness of this therapeutic approach against cancer.
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Keywords: friendly, foe, bacteria, residing, gut, boost, immune, response, tumors, tumor
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07-26-2007 · EurekAlert!
This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published online July 26, 2007, in the JCI, including: A friendly foe: Bacteria residing in the gut boost immune response to tumors; A step forward in our understanding of tissue damage after spinal cord injury; The ABCs of getting rid of excess cholesterol; Activation of liver X receptor-beta lowers cholesterol and reverses atherosclerosis; and others.
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