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New technique to 'see' and protect transplants successful in diabetic animal model

07-29-2007 · EurekAlert!

Researchers at Johns Hopkins have found a way to overcome a major stumbling block to developing successful insulin-cell transplants for people with type I diabetes. They developed a new technique encapsulates the insulin-producing cells in magnetic capsules, using an FDA-approved iron compound with an off-label use, which can be tracked by magnetic resonance imaging (MRI). The product, tested in swine and diabetic mice, also simultaneously avoids rejection by the immune system, likely a major reason for transplant failure.

Keywords: technique, protect, transplants, successful, diabetic, animal, model, transplant

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