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Molecular mechanism of common forms of kidney disease identified
08-01-2007 · EurekAlert!Massachusetts General Hospital researchers have identified a key mechanism underlying proteinuria -- excess protein in the urine which signifies a breakdown in the kidney's filtering process. They have discovered that enzymatic processing of protein called dynamin can cause breakdown of a critical filtering structure called a podocyte, allowing protein to leak out of the bloodstream. The researchers also describe how altered forms of dynamin may be able to block the process and restore kidney function.
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Keywords: molecular, mechanism, forms, kidney, disease, identified, form
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