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Weizmann Institute scientists discover a control mechanism for metastasis
08-08-2007 · EurekAlert!A team of biologists, physicists and doctors at the Weizmann Institute of Science has revealed a cellular mechanism that controls the movement of cells in cancer metastasis. This finding may help predict the progression of metastasis, as well as the design of drugs to prevent it.
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Keywords: weizmann, institute, scientists, discover, control, mechanism, metastasis, scientist, metastasi
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- Weizmann Institute scientists discover a key player in embryonic muscle development
04-11-2007 · EurekAlert!
In the final stage of muscle fiber development, the cell membranes of attached myoblasts open up and fuse together, forming one large, unified cell. It is known how myoblasts identify other myoblasts and cling together, but the way that the cell membranes fuse into one has remained a mystery. Scientists have now discovered that a protein called WIP plays a key role in muscle cell fusion.
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- A gene for metastasis
08-28-2007 · EurekAlert!
Weizmann Institute Scientists reveal the actions of a key player in colorectal cancer.
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- The code of codes -- Scientists discover parallel codes in genes
02-08-2007 · EurekAlert!
Researchers from the Weizmann Institute of Science report the discovery of two new properties of the genetic code. Their work, which appears online in Genome Research, shows that the genetic code -- used by organisms as diverse as reef coral, termites, and humans -- is nearly optimal for encoding signals of any length in parallel to sequences that code for proteins.
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- Novel regulatory mechanism identified for key tumor suppressor p53
11-15-2006 · EurekAlert!
Collaborating scientists from the Wistar Institute in Philadelphia and the Vienna Biocenter in Austria have identified a novel mechanism involved in normal repression of the p53 protein, perhaps the single most important molecule for the control of cancer in humans. The new molecular pathway described in the study suggests intriguing approaches to diagnosing or intervening in the progression of many types of cancer.
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- Forsyth scientists gain new understanding of adult stem cell regulation
08-01-2007 · EurekAlert!
Forsyth Institute scientists have discovered an important mechanism for controlling the behavior of adult stem cells. Research with the flatworm, planaria, found a novel role for the proteins involved in cell-to-cell communication. This work has the potential to help scientists understand the nature of the messages that control stem cell regulation -- such as the message that maintain and tells a stem cell to specialize and to become part of an organ (e.g., liver or skin).
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- Scientists discover novel way to remove iron from ferritin
11-02-2007 · EurekAlert!
A new study led by Children's Hospital Oakland Research Institute senior scientist, Elizabeth Theil, PhD, is the first to suggest that a small protein or heptapeptide could be used to accelerate the removal of iron from ferritin. The results of this study may help scientists develop new medications that dramatically improve the removal of excess iron in patients diagnosed with blood diseases such as B-Thalassemia (Cooley's anemia) or sickle cell disease.
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- Weizmann Institute scientists develop a general 'control switch' for protein activity
06-19-2007 · EurekAlert!
Since malfunctioning proteins can cause disease, the study of protein structure and function can lead to the development of drugs and treatments for numerous disorders. Now, Weizmann scientists have developed a unique "switch" that can control the activity of any protein, raising it several-fold or stopping it almost completely. The method provides researchers with a simple and effective tool for exploring the function of unknown proteins.
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- Weizmann Institute scientists discover genes that can slow cell division and may fight cancer
02-26-2007 · EurekAlert!
When cells begin to divide, they also activate a "braking system" that eventually stops cell division. When this system is faulty, uncontrolled cell division and the growth of cancer can result. Weizmann Institute scientists have identified a number of the genes involved in this braking system. Identification of the exact factors causing uncontrolled cell division may lead to the development of advanced treatments for cancer.
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- Weizmann Institute scientists develop the first molecular keypad lock
01-24-2007 · EurekAlert!
Keypad locks, such as those for preventing auto theft, allow an action to take place only when the right password is entered. Now, a team at the Weizmann Institute of Science has created a molecule that can function as an ultra-miniaturized version of a keypad locking mechanism.
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- Weizmann scientists discover a new line of communication between nervous system cells
06-26-2007 · EurekAlert!
Scientists have now provided a vital insight into the mechanism by which glial cells recognize and myelinate axons -- a discovery that may aid in restoring the normal function of the affected nerve fibers.
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