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The 'female advantage' in kidney disease does not extend to diabetic women

08-08-2007 · EurekAlert!

Studies suggest kidney disease in diabetic women may be result of imbalances in hormonal ratios, not an absolute level of estrogen

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Keywords: female, advantage, kidney, disease, extend, diabetic, women

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    08-08-2007 · EurekAlert!
    In these studies, researchers either added supplemental levels of estrogen/testosterone to rats or castrated/performed ovariectomies in males and females rats, respectively. The studies found that estrogen helped to protect against kidney disease while testosterone proved to be detrimental to kidney health.
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    Findings reported today at EULAR 2007, the Annual European Congress of Rheumatology in Barcelona, Spain, reveal a treatment disparity between female and male patients with rheumatoid arthritis. Data from a study at the Karolinska Institute, Sweden, show that women receive anti-TNFs -- very effective but expensive modern medications against this disease -- at a higher perceived level of disease activity, and when they are reporting more severe pain than their male counterparts.
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  5. Monkey studies parallel WHI findings, point to importance
    06-25-2007 · EurekAlert!
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    Northwestern University researchers have found an enzyme, called "ACE2," may hold the potential to treat diabetic kidney disease, the most common form of kidney disease.The researchers have found low levels of the ACE2 enzyme in kidneys of diabetic mice. When ACE2 was further decreased with an inhibitor drug, kidney disease worsened. Studies are now needed using compounds that increase the level of ACE2 in the kidneys of diabetic mice to see if it reverses or prevents kidney disease.
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  8. Sexual problems of long-term cancer survivors merit more attention
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    Long-term female survivors of genital-tract cancer were pleased with their cancer care but not with the emotional support and information they received about the effects of the disease and treatment on their sexuality. Three out of 5 said their physicians never brought up the effects on sexuality. Women who did report such a conversation were much less likely to have "complex sexual problems" at the time of the survey.
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