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New, more direct pathways from outside the cell-to-cell nuclei discovered
08-10-2007 · EurekAlert!A team of Brooklyn College researchers has shattered a long-held belief that no direct pathway exists between material outside of a cell and the cell nucleus. The cell is the smallest metabolically functional unit of life.
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Keywords: direct, pathways, outside, cell-to-cell, nuclei, discovered, pathway, cell
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- Cell pathway, disease linked to histone action
10-26-2007 · EurekAlert!
In the study a protein was identified that modifies H2A, which in turn regulates normal cell pathways and cell growth. When the function of this protein was blocked in tadpole embryos, the front-to-back body patterning was altered during maturation, according to researchers at the University of Alabama at Birmingham.
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- Stem cell nuclei are soft 'hard drives,' Penn study finds
10-11-2007 · EurekAlert!
Biophysicists at the University of Pennsylvania have discovered that the nuclei of human stem cells are particularly soft and flexible, rather than hard, making it easier for stem cells to migrate through the body and to adopt different shapes, but ultimately to put human genes in the correct nuclear "sector" for proper access and expression.
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- Scientists unlock mystery of embryonic stem cell signaling pathway
03-19-2007 · EurekAlert!
A newly discovered small molecule called IQ-1 plays a key role in preventing embryonic stem cells from differentiating into one or more specific cell types, allowing them to instead continue growing and dividing indefinitely, according to research performed by a team of scientists who have recently joined the stem-cell research efforts at the Keck School of Medicine of the University of Southern California.
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- Penn researchers link cell's protein recycling systems
06-13-2007 · EurekAlert!
Researchers have discovered a molecular link between the cell's two major pathways for breaking down proteins and have succeeded in using this link to rescue neurodegenerative diseases in a simple animal model.
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- Rong Li Lab demonstrates the process of mammalian egg maturation
02-05-2007 · EurekAlert!
The Rong Li lab team has answered an important question about how mammalian eggs undergo maturation through an intricate process of asymmetric cell division. The team discovered a novel pathway by which chromatin exerts command on the cell membrane to produce a specialized machinery used for cell division.
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- 2 heads are better than 1: 2 dysfunctional DNA repair pathways kill tumor cells
04-12-2007 · EurekAlert!
Individuals who inherit one mutant copy of any one of about 12 genes that make the proteins of the Fanconi Anemia pathway are at increased risk of developing cancer. This occurs when the remaining "good" copy of the gene becomes mutated in a specific cell type. However, hope of a new treatment for these cancers has now been provided by a new study indicating that inhibiting the protein ATM can kill these cancer cells.
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- Researchers find pathway that controls cell size and division
07-30-2007 · EurekAlert!
Researchers at Washington University in St. Louis have discovered through genetic analyses a metabolic pathway in bacteria comprised of just three genes, all known to be players in metabolism. This pathway was previously shown to be involved in synthesizing modified membrane lipids but the Petra Levin lab's data indicates it also has a major role in cell division. This is the first identification of a pathway responsible for regulating bacterial cell size.
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- U of M researchers discover a pathway to turn off immune system cells
01-31-2008 · EurekAlert!
University of Minnesota researchers have discovered a new way to turn genes off in human T cells, a type of white blood cell that helps the immune system fight infections.Turning off genes, through a process known as mRNA decay, is important for regulating the body's immune response after fighting infection. This research could lead to development of new drugs that turn off the immune system in patients with autoimmune diseases -- such as rheumatoid arthritis and lupus.
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- UCLA researchers discover novel pathway that may promote immune system balance
06-07-2007 · EurekAlert!
Researchers at UCLA's Jonsson Cancer Center have discovered a novel anti-inflammatory cell signaling pathway that may serve as a vital Yin-Yang mechanism to maintain the delicate balance of immune response.
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- Regulating the nuclear architecture of the cell
12-10-2006 · EurekAlert!
Researchers at the Department of Energy's Lawrence Berkeley National Laboratory have discovered two molecular pathways that regulate the organization of heterochromatin, the nucleolus, and other features of nuclear architecture that maintain genome stability in the fruit fly Drosophila melanogaster.
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