Daily non-political popular news in brief.
Diverse genetic abnormalities lead to NF-κB activation in multiple myeloma
08-13-2007 · EurekAlert!Two new studies may lead to the development of more effective therapies for individuals with multiple myeloma, a common and incurable blood cell cancer. The research, published by Cell Press in the August issue of the journal Cancer Cell, provides new insight into the molecular mechanisms that underlie aberrant NF-κB activity in MM tumor cells and underscores the relevance of the signaling pathway as a target for MM therapy.
Read more »
Keywords: diverse, genetic, abnormalities, lead, nf-, 954, activation, multiple, myeloma, abnormality
« Previous | Next »
Similar news on "Diverse genetic abnormalities lead to NF-κB activation in multiple myeloma":
- Mayo Clinic Cancer Center -- individualizing treatment for multiple myeloma patients
12-10-2006 · EurekAlert!
Researchers at Mayo Clinic Cancer Center, in cooperation with industry partners, have, for the first time, identified tumor specific alterations in the cellular pathway by which the multiple myeloma drug bortezomib (Velcade) works, and they have identified nine new genetic mutations in cancer cells that should increase a patient's chance of responding to the agent.
Similar news · Read more »
- Complex ART procedures more likely to lead to umbilical cord abnormality
07-04-2007 · EurekAlert!
The more complex the assisted reproduction procedure, the more likely the umbilical cord develops in an atypical place or have other abnormalities, a scientist told the 23rd Annual Conference of the European Society of Human Reproduction and Embryology today (Wednesday, July 4). Mrs. Ilse Delbaere, from Ghent University Hospital, Ghent, Belgium, said that the study, including over 4000 twin pregnancies, was the first to examine umbilical cord abnormalities in such a large population.
Similar news · Read more »
- Study examines genetic defects linked to body abnormalities in patients with childhood cancer
01-01-2008 · EurekAlert!
Children with cancer have a higher prevalence of body abnormalities, such as asymmetric lower limbs and curvature of the spine, suggesting that the genetic defect responsible for the abnormality may play a role in the development of cancer, according to a study in the Jan. 2 issue of JAMA.
Similar news · Read more »
- NYU researchers developing molecular delivery vehicles for genetic therapies
11-13-2006 · EurekAlert!
Researchers at New York University are working to develop molecular delivery vehicles that can be used to transport nucleic acids into diverse cell types, which may lead to eventual applications in genetic therapies. Their work is described as part of the cover story in the November 13 issue of the American Chemical Society publication Chemical and Engineering News.
Similar news · Read more »
- Bank on a Cure researchers identify pathways mediating myeloma treatment side effects
12-11-2006 · EurekAlert!
Thalidomide is a widely prescribed treatment for multiple myeloma. However, an estimated 15 to 30 percent of patients suffer venous thromboembolisms (VTEs), blood clots, as a major complication. The Bank On A Cure DNA-bank researchers have identified four gene clusters associated with the VTEs. Identifying the associated single nucleotide polymorphisms (SNPs) for use as markers, may lead to the development of screenings and tailored interventions to prevent these side effects, as a major step toward personalized medicine.
Similar news · Read more »
- Williams Syndrome, The Brain And Music
10-05-2006 · ScienceDaily
Children with Williams syndrome, a rare genetic disorder, just love music and will spend hours listening to or making music. A study by a multi-institutional collaboration of scientists, published in a forthcoming issue of NeuroImage, identified structural abnormalities in a certain brain area of people afflicted with Williams syndrome. This might explain their heightened interest in music and, in some cases, savant-like musical skill.
Similar news · Read more »
- Changes in chromosomal constitution of preimplantation embryos suggest caution in genetic screening
06-18-2007 · EurekAlert!
Embryos that are selected out as abnormal can undergo chromosomal modifications, a scientist will tell the annual conference of the European Society of Human Genetics today, Tuesday, June 19. Tsvia Frumkin, from the Racine IVF unit, LIS Maternity Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, will tell the conference that her team's findings meant that the results of preimplantation genetic screening for chromosomal abnormalities were not always reliable, and should be interpreted with caution.
Similar news · Read more »
- ClC-1 helps mice get a move on
11-15-2007 · EurekAlert!
One symptom of myotonic dystrophy is the inability to voluntarily relax the muscles. DM originates from complex genetic mutations that result in abnormalities of several muscle proteins, including ClC-1. A new study, has established that abnormal inclusion of a specific region of the ClC-1 gene in ClC-1 mRNA has a role in the development of disease in mouse models of DM and developed an approach to correct this, eliminating myotonia.
Similar news · Read more »
- Researchers identify new drug targets for cancer
12-28-2006 · EurekAlert!
Solving a 100-year-old genetic puzzle, researchers at the UCSD School of Medicine have determined that the same genetic mechanism that drives tumor growth can also act as a tumor suppressor. Their findings could lead to new drug targets for cancer therapies.
Similar news · Read more »
- FSU researchers determine a critical factor in workings of proteins
02-14-2007 · EurekAlert!
Scientists know that a better understanding of how proteins bond could lead to more effective treatments for genetic disorders and other life-threatening conditions. Now, a pair of Florida State University researchers' new theory has been proven to accurately predict the association rate for proteins. Their theory is outlined in the February issue of the scientific journal Structure.
Similar news · Read more »
