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Drug interactions with warfarin
08-13-2007 · EurekAlert!This real-world study of prescription data from general practices observed much higher rates of bleeding than those derived from a meta-analysis of randomized clinical trials. The authors write that physicians should be aware of these risks to better assess their patients' therapeutic risk-benefit profiles.
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Keywords: drug, interactions, warfarin, interaction
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- Proteochemometrics achieves better retardants for HIV/Aids
03-14-2007 · EurekAlert!
A new method for analysis of retroviral proteins gives new opportunities to the development of novel retardants for HIV/Aids. The study, which was published in the March issue of PLoS Computational Biology, shows how to in a very exact way analyze the interaction of drug targets with small molecules.
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- Drug-free treatments offer hope for older people in pain
09-10-2007 · EurekAlert!
Mind-body therapies, which focus on the interactions between the mind, body and behavior, and the ways in which emotional, mental, social and behavioral factors can affect health, may be of particular benefit to elderly chronic pain sufferers. A new study published in Pain Medicine provides a structured review of eight mind-body interventions for older people, including progressive muscle relaxation, meditation, hypnosis, tai chi and yoga.
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- Do medical schools affect the way future doctors interact with drug companies?
12-03-2007 · EurekAlert!
Bulk of the approximately $21 billion dollars that pharmaceutical companies spend annually to market their products is targeted to physicians, doctors in training and medical students. Indiana University School of Medicine and the Regenstrief Institute researchers report on interaction between drug companies, medical students and residents and conclude that well-designed seminars, role playing and focused curricula can affect medical student and resident attitudes and behavior toward drug companies.
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- Unexpected protein interaction suggests new ALS drug target
01-24-2008 · EurekAlert!
Discovery of an unexpected protein-protein interaction has led University of Iowa scientists and colleagues to identify a drug that slows the progression of amyotrophic lateral sclerosis in mice and nearly doubles the animals' lifespan. The study is published Jan. 24 online in the Journal of Clinical Investigation.
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- Hidden interactions between predators and prey: evolution causes cryptic dynamics in ecology
09-03-2007 · EurekAlert!
Contemporary rapid evolution in prey and pathogen species masks strong tropic interactions with predators and hosts. These "cryptic dynamics" reveal a need for a new approach to measuring interaction strengths in food webs.
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- Commentary highlights impact of food-cancer drug interactions
07-17-2007 · EurekAlert!
A commentary in the Journal of Clinical Oncology, urges researchers to explore an intriguing approach to reduce the dose and therefore the cost, of oral targeted cancer therapies.
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- Genetics of imatinib resistance in acute lymphoblastic leukemia
08-29-2007 · EurekAlert!
In the Sept. 15 issue of Genes & Development, scientists lend new insights into how an aggressive form of acute lymphoblastic leukemia develops, and how sensitivity to the targeted chemotherapeutic drug, imatinib, can be diminished through interactions between tumor cells and the host microenvironment.
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- Protein sciences
03-08-2007 · EurekAlert!
Protein interactions direct cellular functions and their responses to pathogens and are important therapeutic targets. Scientists from the GSF Research Center for Environment and Health have recently developed a method enabling simultaneous visualization of individual proteins and their interactions in living cells. This is achieved by engineering the proteins to constantly emit red or blue fluorescent signals and to produce an additional yellow fluorescent signal upon interaction.
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- Medication costs infrequently addressed when newly prescribed, UCLA study finds
11-08-2006 · EurekAlert!
A new UCLA study has found that physicians discuss cost and aspects of obtaining newly prescribed medications only about one-third of the time during patient/doctor interactions.But questions about pricing and prescription drug insurance coverage are critical -- the high costs of drugs, including out-of-pocket payouts such as co-payments, are linked to patient non-adherence in maintaining their dosage schedules
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- Genetics determine optimal drug dose of common anticoagulant
08-21-2007 · EurekAlert!
Genetic testing can be used to help personalize the therapeutic dosage of warfarin, a commonly-used anticoagulant, according to research published in the Sep. 1, 2007, issue of Blood, the journal of the American Society of Hematology. This result represents one of the first applications of using an individual's genetic information to guide personal medical care.
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