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HIV is a 'double hit' to the brain
08-15-2007 · EurekAlert!New evidence reported in the August issue of Cell Stem Cell, a publication of Cell Press, offers a novel perspective on how the HIV/AIDS virus leads to learning and memory deficits, a condition known as HIV-associated dementia. A protein found on the surface of the virus not only kills some mature brain cells, as earlier studies had shown, but it also prevents the birth of new brain cells by crippling "adult neural progenitors," the new study finds.
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Keywords: hiv, double, hit, brain
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- HIV is double trouble for brain
09-08-2007 · Science News Online
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- AIDS interferes with stem cells in the brain
08-15-2007 · EurekAlert!
Scientists at the Burnham Institute for Medical Research have discovered how HIV/AIDS disrupts the normal replication of stem cells in the adult brain, preventing new nerve cells from forming. Drs. Stuart Lipton, Marcus Kaul, Shu-ichi Okamoto and colleagues uncovered a novel molecular mechanism that inhibits stem cell proliferation and that could possibly be triggered in other neurodegenerative diseases. These findings were published today online by the journal Cell Stem Cell.
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