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Penn researchers discover new mechanism for viral replication
08-16-2007 · EurekAlert!Researchers have identified a new strategy that Kaposi's Sarcoma Associated Herpesvirus uses to dupe infected cells into replicating its viral genome. This is the first study to directly show that a section of viral DNA can independently draw upon proteins within a host cell to promote its own replication.
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Keywords: penn, researchers, discover, mechanism, viral, replication, researcher
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- Penn researchers discover new target for preventing and treating flu
01-30-2008 · EurekAlert!
Researchers at the University of Pennsylvania School of Medicine have now provided a new strategy for designing drugs that target resistant viral strains of inflenza tupe A by solving the three-dimensional structure of a viral protein called the M2 proton channel. This protein is the molecular receptor for these drugs.
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- Bacterial toxin closes gate on immune response, Penn researchers discover
02-13-2008 · EurekAlert!
Researchers at the University of Pennsylvania School of Medicine have demonstrated that a bacterial toxin from the common bacterium Staphylococcus aureus shuts down the control mechanism of the tunnel, called an ion channel, in immune cell membranes. Shutting down ion channels has long been known to suppress the immune response, and the bacteria may use the toxin to neutralize host defenses against bacteria.
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- Researchers discover mechanism that determines when detailed memories are retained
10-13-2006 · EurekAlert!
The levels of a chemical released by the brain determine how much detail is retained in memories, according to researchers at UC Irvine.
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- Emory researchers identify signaling protein for multiple myeloma
09-10-2007 · EurekAlert!
Researchers at Emory University's Winship Cancer Institute are the first to discover a mechanism that plays a critical role in the multiple myeloma cell cycle and survival. Their research may result in identification of a new therapeutic target for treating multiple myeloma.
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- Viral marker of human migration suspect
10-24-2006 · EurekAlert!
A benign virus previously used as a marker in tracing human migration may be unreliable, according to researchers at Penn State. Results of this study also suggest that some viruses might be undergoing much higher rates of evolution than previously thought.
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- Researchers discover new way to predict survival in older women with lung cancer
11-01-2007 · EurekAlert!
Researchers at UCLA's Jonsson Comprehensive Cancer Center have discovered a novel mechanism to predict survival in older women with early-stage lung cancer. The finding may have significant implications for new treatment approaches.
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- First molecular evidence of body's internal clock in controlling blood pressure
02-19-2007 · EurekAlert!
It has been known for decades that heart attacks and strokes occur most frequently in the early-morning hours. Now, researchers at Penn have provided the first evidence for the role of our body’s internal molecular clock in controlling blood pressure and a mechanism by which this occurs. This report points to the novel possibility of modifying blood pressure and the early-morning risk of heart attack.
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- A taxing issue: How human T-lymphotropic virus
01-30-2008 · EurekAlert!
Researchers have identified a potential new mechanism through which human T-lymphotropic virus type-1 causes leukemia in adults. The findings, published this week in the online open access journal Retrovirology, represent the first time that a reduction in histone protein levels has been linked to viral infection and the development of cancer.
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- Researchers discover key mechanism by which lethal viruses Ebola and Marburg cause disease
10-16-2006 · EurekAlert!
Researchers in the Greene Infectious Disease Laboratory at Columbia University's Mailman School of Public Health, the Centers for Disease Control and Prevention, and the Caribbean Primate Research Center have discovered a key mechanism by which the Filoviruses, Ebola and Marburg, cause disease.
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- Researchers at IRB Barcelona discover a new mechanism that regulates stem cell division
03-05-2007 · EurekAlert!
Stem cells have the extraordinary capacity to divide producing two very distinct cells: one retains stem cell identity and continues to undergo asymmetric division, while the other specializes for a specific function and shows limited capacity to divide. This strategy allows a single stem cell to generate great amounts of tissue during a lifetime. Researchers at IRB Barcelona, have discovered that one of the key factors in asymmetric stem cell division is the behavior of centrosome.
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