science top stories popular news  

Daily non-political popular news in brief.

Vaccine thwarts the tangles of Alzheimer's

08-21-2007 · EurekAlert!

A new study by NYU Medical Center researchers shows for the first time that the immune system can combat the pathological form of tau protein, a key protein implicated in Alzheimer's disease. The researchers, led by Einar Sigurdsson Ph.D., assistant professor of psychiatry and pathology at New York University School of Medicine, created a vaccine in mice that suppresses aggregates of tau. The protein accumulates into harmful tangles in the memory center of the brains of Alzheimer's patients.

Read more »

Keywords: vaccine, thwarts, tangles, alzheimer, thwart, tangle

« Previous | Next »

Similar news on "Vaccine thwarts the tangles of Alzheimer's":

  1. Protein inhibitor tangles with Alzheimer's disease
    02-15-2007 · EurekAlert!
    A hallmark of Alzheimer's disease (AD) is the abnormal accumulation of phosphorylated forms of a protein known as tau. In a new study, Mayo Clinic researchers have now shown in mice that a drug that inhibits the function of the protein Hsp90 (EC102) reduces the amount of phosphorylated tau in the brain. Unlike many drugs, EC102 is able to cross the blood-brain barrier, making it a highly promising therapeutic candidate for AD.
    Similar news · Read more »
  2. JCI table of contents -- June 1, 2007
    06-01-2007 · EurekAlert!
    This release contains summaries, links to PDFs and contact information for the following newsworthy papers to be published online, June 1, 2007, in the JCI, including: Pregnant mom’s exposure to flu vaccine kick-starts fetal immune system; Dietary supplementation with enzyme reverses some kidney disease; Don’t judge a book by its cover: Interleukin-1beta turns out to be helpful in Alzheimer's disease; HIF provides a link between blood and bone development; and others.
    Similar news · Read more »
  3. A possible mechanistic link between stress and the development of Alzheimer tangles
    06-14-2007 · EurekAlert!
    Subjecting mice to repeated emotional stress, the kind we experience in everyday life, may contribute to the accumulation of neurofibrillary tangles, one of the hallmarks of Alzheimer’s disease, report researchers at the Salk Institute for Biological Studies.
    Similar news · Read more »
  4. Transdermal vaccine effective in treating Alzheimer's disease in mouse model
    01-22-2007 · EurekAlert!
    A novel needle-free vaccine approach was found safe and effective in clearing brain-damaging plaques from mice bred to develop Alzheimer's disease. The transdermal vaccination may offer a simple, noninvasive way of preventing or treating Alzheimer'swith less potential for adverse immune reactions.
    Similar news · Read more »
  5. Alzheimer's disease diagnosed 100 years ago today
    11-03-2006 · EurekAlert!
    One hundred years after the first diagnosis of Alzheimer's disease Nov. 3, 1906, researchers at the Yerkes National Primate Research Center, Emory University, are focusing on neuroscience, immunology and vaccine research to better understand how AD develops and progresses as well as to advance the treatment and prevention of this progressive brain disorder. AD, which currently affects 20 million Americans, gradually destroys memory and the ability to learn, reason, make judgments and communicate.
    Similar news · Read more »
  6. An Alzheimer's vaccine?
    11-11-2007 · EurekAlert!
    A new research study from the Oklahoma Medical Research Foundation shows that immunization could offer a way to blunt or even prevent the deadly, memory-robbing disease.
    Similar news · Read more »
  7. Paving the way toward a vaccine against Alzheimer's disease
    06-21-2007 · EurekAlert!
    Scientists have provided new details about how proteins used to destroy bacteria and viruses may help treat Alzheimer's disease. Gunnar K. Gouras, associate professor of neurology and neuroscience at Weill Medical College of Cornell University, New York, and colleagues provide new insights into how these proteins, called antibodies, reduce the main hallmarks of Alzheimer's disease and raise hopes for a vaccine against the disease.
    Similar news · Read more »
  8. Targeting tau: Inflammation study suggests new approach for fighting Alzheimer's
    02-01-2007 · EurekAlert!
    Researchers at the University of Pennsylvania School of Medicine have shown that impaired function and loss of synapses in the hippocampus of a mouse form of Alzheimer's disease (AD) is related to the activation of immune cells called microglia, which cause inflammation. These events precede the formation of tangles -- twisted fibers of tau protein that build up inside nerve cells -- a hallmark of advanced AD.
    Similar news · Read more »
  9. Researchers use novel three-dimensional imaging technique
    10-24-2006 · EurekAlert!
    Using an innovative three-dimensional imaging technique, a team of UCLA researchers have tracked how Alzheimer's disease spreads through the hippocampus -- the area of the brain linked with memory -- in a pattern consistent with the known trajectory of neurofibrilliary tangle dissemination, an accumulation of diseased proteins in the brain cells. They found that three areas within the hippocampus of Alzheimer's patients show more atrophy compared with those in patients having amnestic mild cognitive impairment.
    Similar news · Read more »
  10. New imaging compound might 'see' Alzheimer's earlier
    12-20-2006 · EurekAlert!
    A new imaging molecule that can map plaques and tangles in the brains of people with Alzheimer's disease could eventually lead to earlier diagnosis of the devastating disease, according to a study funded by the National Instiutute on Aging, part of the National Institutes of Health.
    Similar news · Read more »