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New weapon to fight leukemia

A new study indicates that the drug FTY720 prevents disease in a mouse model of two leukemias -- blast crisis chronic myeloid leukemia and acute lymphocytic leukemia -- caused by the cancer protein BCR-ABL. As the drug also induced cell lines from humans with these leukemias to die in vitro the authors suggest that FTY720 should be considered by researchers and clinicians developing new approaches to treat CML-BC and ALL.

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Keywords: weapon, fight, leukemia

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1. JCI table of contents: Aug. 23, 2007
   08-23-2007 · EurekAlert!
   This release contains summaries, links to PDFs and contact information for the following newsworthy papers to be published online, Aug. 23, 2007, in the JCI, including: New weapon to fight leukemia; Inhaling helps heal liver transplant recipients; Being fat needn't be all bad news; DNA provides clues to outcome in patients with liver cancer; Risk factor for heart disease: Just say NO; Building muscle requires Foxo1; and others.
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