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Scientists identify embryonic stem cells by appearance alone

08-27-2007 · EurekAlert!

Scientist can now identify pluripotent stem cells based solely on their physical appearance.

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Keywords: scientists, identify, embryonic, stem, cells, appearance, alone, scientist, cell

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  1. Scientists identify a mouse embryonic stem cell more like our own
    06-27-2007 · EurekAlert!
    Scientists have discovered a new type of mouse embryonic stem cell that is the closest counterpart yet to human embryonic stem cells, the National Institutes of Health announced today. The cells are expected to serve as an improved model for human ES cells in studies of regeneration, disease pathology and basic stem cell biology.
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  2. Mass. General researchers identify master cardiac stem cell
    11-22-2006 · EurekAlert!
    Researchers from the Massachusetts General Hospital Cardiovascular Research Center have discovered what appears to be a master cardiac stem cell, capable of differentiating into the three major cell types of the mammalian heart. In a report to appear in the journal Cell, receiving early online release, they describe identifying these progenitor cells in mice, cloning them from embryonic stem cells, and showing that cloned cells can differentiate into cardiac muscle, smooth muscle or endothelial cells.
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  3. Gene Key To Taste Bud Development Identified
    10-02-2006 · ScienceDaily
    Scientists have identified a gene that controls the development of taste buds. The gene, SOX2, stimulates stem cells on the surface of the embryonic tongue and in the back of the mouth to transform into taste buds, according to the researchers. Stem cells are immature cells that can develop into several different cell types depending on what biochemical instructions they receive.
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  4. Chemical cues turn embryonic stem cells into cerebellar neurons
    03-14-2007 · EurekAlert!
    Rockefeller University scientists show that embryonic stem cells implanted in the brain appear to develop into fully differentiated granule neurons, the most plentiful neuron in the cerebellum. The findings are a step toward understanding how embryonic stem cells could be regulated in vivo and ultimately used for cell replacement therapy, especially after childhood tumors, in the central nervous system.
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  5. Cancer stem cells can go it alone
    06-11-2007 · EurekAlert!
    At the heart of most, if not all cancers, lie a handful of wayward stem cells that feed the ever growing tumor mass, but their scarcity make it difficult for scientists to study them. Now, times of plenty may lie ahead as a breast cancer cell line -- established long ago -- turned out to behave a lot like cancer stem cells.
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  6. Human embryonic stem cell lines created that avoid immune rejection
    12-20-2007 · EurekAlert!
    In a groundbreaking experiment published in Cloning & Stem Cells, scientists from International Stem Cell Corp. derived four unique embryonic stem cell lines that open the door for the creation of therapeutic cells that will not provoke an immune reaction in large segments of the population. The stem cell lines are "HLA-homozygous," meaning that they have a simple genetic profile in the critical areas of the DNA that code for immune rejection.
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  7. Scientists discover stage at which an embryonic cell is fated to become a stem cell
    01-10-2007 · EurekAlert!
    Cambridge scientists have discovered the stage at which some of the cells of a fertilized mammalian egg are fated to develop into stem cells and why this occurs. The findings of the study, which overturn the long-held belief that cells are the same until the fourth cleavage (division) of the embryo, are reported in today's edition of Nature.
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  8. Scientists unlock mystery of embryonic stem cell signaling pathway
    03-19-2007 · EurekAlert!
    A newly discovered small molecule called IQ-1 plays a key role in preventing embryonic stem cells from differentiating into one or more specific cell types, allowing them to instead continue growing and dividing indefinitely, according to research performed by a team of scientists who have recently joined the stem-cell research efforts at the Keck School of Medicine of the University of Southern California.
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  9. Scientists identify synthetic compound that keeps stem cells young
    10-31-2006 · EurekAlert!
    A team of scientists from the Scripps Research Institute, the Genomics Institute of the Novartis Research Foundation and the Max Planck Institute for Molecular Biomedicine has discovered a new synthetic compound that can support growth and self-renewal of mouse embryonic stem cells, offering a simple alternative to current growth conditions that may vary batch-to-batch and confuse experimental results.
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  10. Not all embryonic stem cell lines are created equal
    08-06-2007 · EurekAlert!
    When it comes to generating neurons, researchers have found that not all embryonic stem cell lines are equal. In comparing neurons generated from two NIH-approved embryonic stem cell lines, scientists have uncovered significant differences in the mature, functioning neurons generated from each line. The discovery implies that culture conditions during ES cell generation -- which have yet to be identified -- can influence the developmental properties of human ES cells.
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