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U-M researchers dispute widely held ideas about stem cells

How do adult stem cells protect themselves from accumulating genetic mutations that can lead to cancer?

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Similar news on "U-M researchers dispute widely held ideas about stem cells":

1. Neural stem cells lend the brain a surprising capacity for self-repair
   12-14-2006 · EurekAlert!
   The brain contains stem cells with a surprising capacity for repair, researchers report in the Dec. 15 issue of the journal Cell, published by Cell Press. The novel insight into the brain's natural ability to heal might ultimately have clinical implications for the treatment of brain damage, according to the researchers.
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2. Loss of stem cells correlates with premature aging in animal study
   06-06-2007 · EurekAlert!
   Researchers at the Abramson Family Cancer Research Institute of the University of Pennsylvania have found that deleting a gene important in embryo development leads to premature aging and loss of stem cell reservoirs in adult mice. This gene, ATR, is essential for the body's response to damaged DNA, and mutations in proteins in the DNA damage response underlie certain types of cancer and other disorders in humans.
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3. Researchers reveal repressor protein blocks neural stem cell development
   10-10-2007 · EurekAlert!
   A protein known to repress gene transcription at the molecular level in a variety of processes also blocks embryonic neural stem cells from differentiating into neurons, according to a study by University of California, San Diego and Howard Hughes Medical Institute researchers published online Oct. 10 in Nature.
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4. 'Mini transplant' patients' outcomes similar using related and unrelated donor cells
   12-03-2007 · EurekAlert!
   People who undergo nonmyeloablative stem-cell transplants, or 'mini transplants,' for leukemia, lymphoma and other blood cancers have comparable outcomes regardless of whether they receive tissue-matched stem cells from a related or unrelated donor, according to new findings by researchers at Fred Hutchinson Cancer Research Center.
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5. MIT corrects sickle-cell anemia in mice
   12-07-2007 · Massachusetts Institute of Technology (MIT)
   MIT researchers have successfully treated mice with sickle-cell anemia in a process that begins by directly reprogramming the mice's own cells to an embryonic-stem-cell-like state, without the use of eggs.
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6. Gene Key To Taste Bud Development Identified
   10-02-2006 · ScienceDaily
   Scientists have identified a gene that controls the development of taste buds. The gene, SOX2, stimulates stem cells on the surface of the embryonic tongue and in the back of the mouth to transform into taste buds, according to the researchers. Stem cells are immature cells that can develop into several different cell types depending on what biochemical instructions they receive.
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7. Researchers Find Smallest Cellular Genome
   10-14-2006 · ScienceDaily
   The smallest collection of genes ever found for a cellular organism comes from tiny symbiotic bacteria that live inside special cells inside a small insect. Just 182 genes, the 160-kilobase genome could revise ideas about what's needed for a cell to work. The finding also provides new insight into bacterial evolution.
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8. Mass. General researchers identify master cardiac stem cell
   11-22-2006 · EurekAlert!
   Researchers from the Massachusetts General Hospital Cardiovascular Research Center have discovered what appears to be a master cardiac stem cell, capable of differentiating into the three major cell types of the mammalian heart. In a report to appear in the journal Cell, receiving early online release, they describe identifying these progenitor cells in mice, cloning them from embryonic stem cells, and showing that cloned cells can differentiate into cardiac muscle, smooth muscle or endothelial cells.
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9. Human stem cell transplants mature into neurons and make contacts in rat spinal cord
   02-13-2007 · EurekAlert!
   Human nerve stem cells transplanted into rats' damaged spinal cords have survived, grown and in some cases connected with the rats' own spinal cord cells in a Johns Hopkins laboratory, overturning the long-held notion that spinal cords won't allow nerve repair.
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10. When smell cells fail they call in stem cell reserves
    04-29-2007 · EurekAlert!
    Hopkins researchers have identified a backup supply of stem cells that can repair the most severe damage to the nerves responsible for our sense of smell. These reservists normally lie around and do nothing, but when neighboring cells die, the scientists say, the stem cells jump into action. A report on the discovery will appear online next week in Nature Neuroscience.
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