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Bad Alzheimer's proteins sow disorder in the brain

Alzheimer's disease may start with a single abnormal protein that spoils other proteins nearby.

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Keywords: bad, alzheimer, proteins, sow, disorder, brain, protein

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1. High Dopamine Transporter Levels Not Correlated with ADHD
   11-29-2006 · Brookhaven National Laboratory
   Results from a brain-imaging study conducted at the U.S. Department of Energy's Brookhaven National Laboratory in collaboration with Mount Sinai School of Medicine in New York indicate that levels of a brain protein proposed as a diagnostic marker for attention-deficit hyperactivity disorder (ADHD) are not positively correlated with the disease. In fact, the study found lower levels of these "dopamine transporter" proteins in certain brain regions of ADHD patients compared with controls.
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2. Blocking immune cell action increases Alzheimer's-associated protein deposits
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   The immune system's response against amyloid-beta, the protein that forms plaques in the brains of patients with Alzheimer's disease, appears to protect the brain from damage in early stages of the devastating neurological disorder. A report from Massachusetts General Hospital researchers finds that lack of a protein required for recruitment of the brain's primary immune cell led to increased amyloid-beta deposits and earlier death in a mouse model of Alzheimer's disease.
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3. Alzheimer's molecule is a smart speed bump on the nerve-cell transport highway
   01-17-2008 · EurekAlert!
   Researchers at the University of Pennsylvania School of Medicine discovered that proteins carrying chemical cargo in nerve cells react differently when exposed to the tau protein, which plays an important role in Alzheimer's disease.
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4. New protein synthesis not essential to memory formation
   07-26-2007 · EurekAlert!
   New research from the University of Illinois challenges the premise that the brain must build new proteins in response to an experience for that experience to be recorded in long-term memory.The findings, published in the Proceedings of the National Academy of Sciences, could alter basic assumptions about the role of protein synthesis in memory formation.
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5. New insight into brain disorders
   02-28-2007 · EurekAlert!
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6. Scientists identify new strategy for preventing acute and chronic brain disease
   05-03-2007 · EurekAlert!
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   06-17-2007 · EurekAlert!
   An enzyme involved in the formation of the amyloid-beta protein associated with Alzheimer's disease can also alter the mechanism by which signals are transmitted between brain cells, the disruption of which can cause seizures. These findings from researchers at the MassGeneral Institute for Neurodegenerative Disorders may explain the increased incidence of seizures in Alzheimer's patients, and suggest that potential treatments that block this enzyme may alleviate their occurrence
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8. Blood pressure drug curbs brain damage from PTSD
   11-06-2007 · EurekAlert!
   A drug used to treat high blood pressure and enlargement of the prostate may protect the brain from damage caused by post-traumatic stress disorder, Alzheimer's disease, depression and schizophrenia. Prazosin, also prescribed as an antipsychotic medication, appears to block the increase of steroid hormones known as glucocorticoids, Portland researchers have found. Elevated levels of glucocorticoids are associated with atrophy in nerve branches where impulses are transmitted, and even nerve cell death, in the hippocampus.
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10. Study shows cats can succumb to feline Alzheimer's disease
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