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£1M project to investigate tumour growth molecules

Professor Ravi Acharya from the Department of Biology & Biochemistry has been awarded more than £1 million to study a group of molecules involved in the growth of tumours.

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Keywords: project, investigate, tumour, growth, molecules, molecule

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1. Study suggests existing drugs may be useful in treating brain tumors
   10-15-2007 · EurekAlert!
   Scientists have shown how developing brain tumors can turn an encounter with a signaling molecule from a fatal experience for the tumor cells into a cue for their own growth and multiplication. The transformation relies on two molecules that can be modified with existing drugs, opening the possibility of using them to treat brain tumors.
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2. Researchers investigate ways to detect lupus-associated kidney disease
   11-13-2007 · EurekAlert!
   High urinary levels of certain molecules might have the potential to serve as biomarkers for a potentially life-shortening kidney ailment caused by the autoimmune disease lupus, UT Southwestern Medical Center researchers have found.
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3. Scientists discover new class of RNA
   01-11-2007 · Massachusetts Institute of Technology (MIT)
   With the discoveries of RNA interference and microRNAs, the RNA molecule has been catapulted to stardom as a major player in genomic activity. Now a team of scientists led by an MIT professor has discovered an entirely new class of RNA molecules.
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4. New Brandeis research sheds light on memory by erasing it
   05-08-2007 · EurekAlert!
   For years, scientists have studied the molecular basis of memory storage, trying to find the molecules that store memory, just as DNA stores genetic memory. In an important study published this week in the Journal of Neuroscience, Brandeis University researchers report for the first time that memory storage can be induced and then biochemically erased in slices of rat hippocampus by manipulating a so-called "memory molecule," a protein kinase known as CaMKII.
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5. Desktop device generates and traps rare ultracold molecules
   12-12-2007 · EurekAlert!
   Physicists at the University of Rochester have combined an atom-chiller with a molecule trap, creating for the first time a device that can generate and trap huge numbers of elusive-yet-valuable ultracold polar molecules. Scientists believe ultracold polar molecules will allow them to create exotic artificial crystals and stable quantum computers.
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6. Waste not, want not: Role for caveolin-3 in muscular dystrophy
   10-12-2006 · EurekAlert!
   Muscular dystrophies are characterized by skeletal muscle weakness due to muscle fiber wasting and loss. Kawasaki Medical School researchers now show in the JCI that mice lacking caveolin-3 -- a protein that helps form a scaffold onto which other signaling molecules assemble at the cell plasma membrane -- increases the intracellular activity of myostatin, an inhibitor of muscle growth, and leads to muscle wasting. Myostatin inhibition may have potential as a therapy for certain muscular dystrophies.
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7. Targeting nerve growth factor may cure liver cancer
   09-05-2007 · EurekAlert!
   Biologists led by Dr. Serafino from the National Research Council of Italy published their surprising discovery that NGF and its receptor were aberrantly expressed in the liver of the patients troubled with liver cirrhosis and/or hepatocellular carcinoma (HCC). These two molecules are not expressed in the liver of healthy people. Published in the October 7 issue of the World Journal of gastroenterology, this article brings a bright future for devising a cure for HCC.
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8. Bone marrow cell transplants help nerve regeneration
   12-04-2007 · EurekAlert!
   Researchers inserted bone marrow-derived cells (BMCs) into 15mm silicon tubes and subsequently implanted into animal models at sites intended for nerve regeneration. When the BMCs were nourished with bioengineered additives -- such as growth factors and cell adhesion molecules -- the BMCs differentiated into cells with characteristics of Schwann cells -- a variety of neural cell providing insulating myelin around the axons of peripheral nerve cells. The work represents a further step in developing artificial nerves.
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9. Researchers investigate ways to detect lupus-associated kidney disease
   11-13-2007 · UT Southwestern Medical Center
   High urinary levels of certain molecules might have the potential to serve as biomarkers for a potentially life-shortening kidney ailment caused by the autoimmune disease lupus, UT Southwestern Medical Center researchers have found.
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10. Walking molecule now carries packages
    01-18-2007 · EurekAlert!
    A research team, led by UC Riverside's Ludwig Bartels, was the first to design a molecule that can move in a straight line on a flat surface. Now this team has found a way to attach cargo: two CO2 molecules, making the nano-walker a molecule carrier.
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