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First individual genome sequence published
09-03-2007 · EurekAlert!Comparison of the DNA sequence of an individual human from the reference sequence reveals a surprising amount of difference.
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- Looking to a new era in bee research
10-27-2006 · EurekAlert!
A respected UK entomology journal, Insect Molecular Biology, today publishes its Honey Bee Genome Special Issue, timed to coincide with the release of the long-awaited Honey Bee Genome Sequence, published earlier this week in Nature magazine.
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- DOE JGI Community Sequencing Program delivers first moss genome
12-13-2007 · EurekAlert!
Messages from nearly a half-billion years ago, conveyed via the inventory of genes sequenced from a present-day moss, provide clues about the earliest colonization of dry land by plants. The US Department of Energy Joint Genome Institute, was among the leaders of an international effort to complete the sequence of the first nonvascular land plant, the moss Physcomitrella patens, published Dec. 13 online in Science Express.
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- 454 Sequencing: Science paper describes a novel, highly efficient method of sequencing ancient DNA
09-27-2007 · EurekAlert!
The study demonstrates the efficacy of this new method by employing 454 Sequencing to sequence the entire mitochondria from 10 individual woolly mammoths. Several of the hair samples investigated were up to 50,000 years old with one sample being stored in a Russian museum for 200 years at room temperature. To put this new study in perspective, only seven mitochondrial genomes from extinct animals had been previously published.
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- Scientists complete genome sequence of fungus responsible for dandruff, skin disorders
11-06-2007 · EurekAlert!
Scientists from P&G Beauty announced that they successfully sequenced the complete genome for Malassezia globosa, a naturally-occurring fungus responsible for the onset of dandruff and other skin conditions in humans. Results of the genome sequencing are published in today's online edition of Proceedings of the National Academy of Sciences.
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- As personal genomics stands poised to go mainstream, researchers urge caution
09-20-2007 · EurekAlert!
Imagine this: you visit your clinician, undergo genetic testing and then you are handed a miniature hard drive containing your personal genome sequence, which is subsequently uploaded onto publicly accessible databases. This may sound like science fiction, but it is scientific fact, and it is already happening. In an article published in the journal Science, University of Alberta researcher Tim Caulfield and co-authors highlight the need to proceed cautiously when it comes to personal genomics.
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- 454 Life Sciences and Baylor College of Medicine complete sequencing of DNA pioneer
05-31-2007 · EurekAlert!
454 Life Sciences Corporation, in collaboration with scientists at the Human Genome Sequencing Center, Baylor College of Medicine, announced today in Houston, Texas, the completion of a project to sequence the genome of James D. Watson, Ph.D., co-discoverer of the double-helix structure of DNA. The mapping of Dr. Watson's genome was completed using the Genome Sequencer FLX system, and marks the first individual genome to be sequenced for less than $1 million.
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- Tough enough for Mars, but deinococcus is from Earth
09-25-2007 · EurekAlert!
Results of a recent study titled "Deinococcus geothermalis: The Pool of Extreme Radiation Resistance Genes Shrinks," will be published in the Sept. 26 edition of PLoS ONE. The study headed by Michael J. Daly, Ph.D., associate professor at the Uniformed Services University of the Health Sciences, department of pathology, reports the whole-genome sequence of Deinococcus geothermalis, which is only the second for an extremely radiation- and desiccation-resistant bacterium.
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- Which genome variants matter?
02-08-2007 · EurekAlert!
Findings published in Science will accelerate the search for genes involved in human disease. This first genome-wide view shows that activity of more than 1000 genes is affected by sequence variation. This is an important step to understanding links between genes and disease for individuals, and across populations. By defining those genetic variants with a biological effect, the results will help prioritise regions of the genome that are investigated for association with disease.
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- Microarray sequence capture speeds large-scale resequencing of targeted genomic regions
10-14-2007 · EurekAlert!
Researchers at Baylor College of Medicine and Roche NimbleGen Inc. today have published details of a highly efficient and cost-effective method for capturing targeted regions of the genome via NimbleChip microarrays in preparation for high-throughput 454 Sequencing. The technology, called 'sequence capture,' enables fast and accurate enrichment of thousands of selected genomic regions, either contiguous or dispersed, such as segments of chromosomes or all genes or exons. The study appears online in the journal Nature Methods.
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- Analysis of rhesus monkey genome uncovers genetic differences with humans, chimps
04-12-2007 · EurekAlert!
An international consortium of researchers has published the genome sequence of the rhesus macaque monkey and aligned it with the chimpanzee and human genomes. Published April 13 in a special section of the journal Science, the analysis reveals that the three primate species share about 93 percent of their DNA, yet have some significant differences among their genes.
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