science top stories popular news  

Daily non-political popular news in brief.

Enzyme alerts cell's powerful army to repair DNA damage

09-05-2007 · EurekAlert!

Each day cells detect and repair daily assaults to our DNA. University of Michigan researchers have discovered that a well-known enzyme scans genes for damage and alerts the major cancer suppressor protein p53. The finding has implications for treating cancer and neurological diseases.

Read more »

Keywords: enzyme, alerts, cell, powerful, army, repair, dna, damage, alert

« Previous | Next »

Similar news on "Enzyme alerts cell's powerful army to repair DNA damage":

  1. Protein averts cell suicide but might contribute to cancer
    03-29-2007 · EurekAlert!
    Scientists have discovered how an unusual protein helps a cell bypass damage when making new DNA, thereby averting the cell's self-destruction. But they also discovered that this protein, an enzyme called Dpo4, often makes errors when copying the genomic DNA sequence that later might cause the cell to become cancerous.
    Similar news · Read more »
  2. Age-related changes in DNA repair illuminate the connection between age and genetic damage
    10-23-2006 · EurekAlert!
    Researchers have uncovered a new way in which the aging process is linked to DNA damage -- which occurs normally as a result of cell metabolism and environmental influences -- and the various ways in which cells repair that damage. In the new work, researchers found that cells in young fruit flies make use of a different mix of molecular DNA-repair mechanisms compared to cells in older flies.
    Similar news · Read more »
  3. Where broken DNA is repaired
    08-02-2007 · EurekAlert!
    Intricate DNA repair mechanisms in cell nuclei are constantly working to fix damaged DNA, but for mammalian cells, exactly where the repair work happens has been an unanswered question. By comparing computer models of damaged human DNA with microscopic images of radiation-induced damage in human cells, researchers at Lawrence Berkeley National Laboratory and their colleagues have found evidence for specific regions where broken DNA is concentrated for repair.
    Similar news · Read more »
  4. Nanoscale microscope sheds first light on gene repair
    11-13-2006 · EurekAlert!
    Proteins called H2AX act as "first aid" to DNA, among other roles. For the first time, scientists using the world's most powerful light microscope (the only one of its kind in the Americas) have seen how H2AX is distributed in the cell nucleus: in clusters, directing the first aid/repair after DNA injuries to the region where it is really needed.
    Similar news · Read more »
  5. DNA repair teams' motto: 'To protect and serve'
    11-16-2006 · EurekAlert!
    When you dial 911 you expect rescuers to pull up at your front door, unload and get busy -- not park the truck down the street and eat donuts. It's the same for a cell -- just before it divides, it recruits protein complexes that repair breakage that may have occurred along your 46 chromosomes. Without repair, damage caused by smoking, chemical mutagens, or radiation might be passed on to the next generation.
    Similar news · Read more »
  6. Faulty gene linked to prostate cancer risk
    10-30-2006 · EurekAlert!
    Missing sections of a gene, which programs the manufacture of a chemical to alert the body to DNA damage, almost doubles the risk of prostate cancer, reveals research published ahead of print in the Journal of Medical Genetics.
    Similar news · Read more »
  7. Analysis reveals extent of DNA repair army
    05-24-2007 · EurekAlert!
    A new database developed by a team of researchers from the Howard Hughes Medical Institute is providing the first detailed portrait of the army of more than 700 proteins that helps maintain DNA's integrity.
    Similar news · Read more »
  8. Getting to the heart of the heart
    11-22-2006 · EurekAlert!
    Helping to change scientists' thinking about how the heart is formed, investigators at Children's Hospital Boston have identified a type of stem cell that gives rise to at least two different cell types that make up the heart's tissues. The findings, to be published in the Dec. 15 Cell, bring researchers a step closer to being able to regenerate tissues to repair congenital heart defects in children and damage caused by heart attacks in adults.
    Similar news · Read more »
  9. Loss of stem cells correlates with premature aging in animal study
    06-06-2007 · EurekAlert!
    Researchers at the Abramson Family Cancer Research Institute of the University of Pennsylvania have found that deleting a gene important in embryo development leads to premature aging and loss of stem cell reservoirs in adult mice. This gene, ATR, is essential for the body's response to damaged DNA, and mutations in proteins in the DNA damage response underlie certain types of cancer and other disorders in humans.
    Similar news · Read more »
  10. Neural stem cells lend the brain a surprising capacity for self-repair
    12-14-2006 · EurekAlert!
    The brain contains stem cells with a surprising capacity for repair, researchers report in the Dec. 15 issue of the journal Cell, published by Cell Press. The novel insight into the brain's natural ability to heal might ultimately have clinical implications for the treatment of brain damage, according to the researchers.
    Similar news · Read more »