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New insight into the mechanisms of voltage sensing and transduction in biological processes
09-14-2007 · EurekAlert!The voltage sensor of voltage-gated ion channels is a conserved protein domain that senses millivolt changes in transmembrane potential, to regulate ion permeation through the channel. A recently discovered protein, Ci-VSP, has a voltage sensor that is coupled not to an ion channel but to a phosphatidylinositide phosphosphatase, the activity of which depends on membrane potential.
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Keywords: insight, mechanisms, voltage, sensing, transduction, biological, processes, mechanism, processe
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